| Type | Description |
|---|---|
| Definition | microtubule-actin crosslinking factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:24:00 | Deficiency of Macf1 in osterix expressing cells decreases bone formation by Bmp2/Smad/Runx2 pathway. | 31709715 |
| 2021-03-06 13:25:00 | Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation. | 32143362 |
| 2020-10-24 14:06:00 | The cytoskeletal crosslinking protein MACF1 is dispensable for thrombus formation and hemostasis. | 31118482 |
| 2020-05-30 13:24:00 | MACF1 positively regulates osteoclast differentiation via the Akt/GSK3beta/NFATc1 signalling pathway. | 31260729 |
| 2019-05-18 11:19:00 | mechanical unloading decreases MACF1 expression, and MACF1 up-regulates osteoblast proliferation through enhancing beta-catenin signaling. This study has thus provided a mechanism for mechanical unloading-induced inhibited osteoblast proliferation. | 29219183 |
| Type | IDs |
|---|---|
| Synonymous | ABP620, Acf7, Aclp7, MACF, R74989, mKIAA0465 |
| Gene |
UniProtKB-ID:
A0A0A0MQA6_MOUSE,
E9PVY8_MOUSE
UniprotKB:
A0A0A0MQA6,
E9PVY8
UniParc:
UPI00001C6B97,
UPI0000609071
EMBL:
AL606932,
AL606918
Ensembl:
ENSMUSG00000028649
KO:
mmu:11426
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000082108,
ENSMUST00000097897
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080755,
ENSMUSP00000095507
RefSeq:
XP_036019486.1,
XP_036019483.1,
XP_030108957.1,
NP_001186065.1,
XP_036019485.1,
XP_036019484.1,
XP_011238718.2,
XP_036019488.1,
XP_036019490.1,
XP_036019487.1,
XP_036019492.1,
XP_030108956.1,
XP_011238719.2,
XP_036019491.1,
NP_001186066.1,
XP_011238713.2,
XP_036019493.1,
XP_036019489.1
|
| Others |
UniRef100:
UniRef100_A0A0A0MQA6,
UniRef100_E9PVY8
UniRef90:
UniRef90_Q9QXZ0,
UniRef90_A0A0A0MQA6
UniRef50:
UniRef50_Q9UPN3-2,
UniRef50_Q9QXZ0
UniGene:
Mm.402299,
Mm.485351
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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