| Type | Description |
|---|---|
| Definition | nephronectin |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:36:00 | Npnt gene expression is regulated by extracellular inorganic Phosphate via Pit and Fgfrs. | 30341591 |
| 2020-05-09 10:49:00 | we show that a novel truncated form of NPNT is found in small extracellular vesicles (sEVs) derived from breast cancer cells. | 30707844 |
| 2019-09-21 10:56:00 | Nephronectin is produced by podocytes and deposited into the GBM. It colocalized with alpha8beta1 integrin to novel, specialized adhesion structures at sites of mesangial cell protrusion at the base of the capillary loops. Nephronectin loss disrupted these structures, mislocalizating alpha8beta1, and caused mesangial sclerosis. | 29335243 |
| 2018-12-22 12:01:00 | Results show that Npnt is highly expressed in tooth germ, and localized in the basement membrane between dental epithelium and mesenchyme. The study indicates that Npnt plays a critical scaffold role in dental epithelial stem cell differentiation and proliferation, and regulates Sox2 expression during tooth development. | 28345658 |
| 2018-10-27 10:12:00 | Low Nephronectin expression is associated with Metastatic Breast Carcinoma. | 28842827 |
| Type | IDs |
|---|---|
| Synonymous | 1110009H02Rik, AA682063, AI314031, Nctn, POEM |
| Gene |
UniProtKB-ID:
NPNT_MOUSE,
D3YTX1_MOUSE,
Q3TYB4_MOUSE
UniprotKB:
Q91V88,
D3YTX1,
Q3TYB4
UniParc:
UPI00000E7334,
UPI00005AD225,
UPI0000029807,
UPI0000028E30,
UPI000161173F,
UPI00000E8880
EMBL:
AY035899,
AC139942,
AK158764,
BC068308,
AY035898,
AF397007,
AB059656,
AK050484,
BC046642,
AF397008
Ensembl:
ENSMUSG00000040998
KO:
mmu:114249
|
| Nucleutide sequences |
EMBL-CDS:
AAH46642.1,
AAH68308.1,
AAK96010.1,
AAK84391.1,
BAB69692.1,
AAK96011.1,
BAC34283.1,
AAK84392.1,
BAE34649.1
Ensembl_TRS:
ENSMUST00000117164,
ENSMUST00000042744,
ENSMUST00000042729,
ENSMUST00000093971,
ENSMUST00000117456
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040684,
ENSMUSP00000040071,
ENSMUSP00000113419,
ENSMUSP00000091505,
ENSMUSP00000112816
RefSeq:
NP_001274031.1,
XP_006500978.1,
NP_001274030.1,
NP_001274032.1,
NP_001025007.1,
NP_277060.2
|
| Others |
UniRef100:
UniRef100_Q91V88,
UniRef100_D3YTX1,
UniRef100_Q3TYB4
UniRef90:
UniRef90_Q91V88-3,
UniRef90_Q91V88
UniRef50:
UniRef50_Q91V88-3,
UniRef50_Q91V88
UniGene:
Mm.279310
CCDS:
CCDS17846.1,
CCDS17845.1,
CCDS71322.1,
CCDS71323.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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