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11423 Ache

11423

Ache

acetylcholinesterase

protein-coding

Mus musculus

基因描述

Type Description
Definition acetylcholinesterase

研究结论

Date Results Publications
2020-10-03 12:50:00 Neurological sequel of chronic kidney disease: From diminished Acetylcholinesterase activity to mitochondrial dysfunctions, oxidative stress and inflammation in mice brain. 30816118
2019-08-24 12:19:00 Loss of acetylcholinesterase activity with mitochondrial dysfunction is associated with hypercholesterolemia. 29263397
2019-04-13 11:03:00 In melanoma, MITF overexpression induced ACHE transcription, and mutation of an E-box site in human ACHE promoter blocked this induction 30076217
2017-12-16 11:19:00 Results indicate that direct inhibition of acetylcholinesterase activity and up-regulation of m1 muscarinic acetylcholine receptor expression in the striatum might contribute to the beneficial effects of alpha-asarone on locomotor hyperactivity in Fmr1 knock out mice. 27316341
2017-07-29 11:52:00 Data show that 1-month of oral treatment with beta-asarone reduces AChE, Abeta42, APP and Beclin-1 levels and alleviates some behavioral impairments by inhibiting the autophagy via regulating the PI3K/Akt/mTOR pathway in APP/PS1 transgenic mice. The results further support the exploration of beta-asarone as a possible disease-modifying agent for the treatment of Alzheimer's disease. 27737765

名称对应

Type IDs
Gene
UniProtKB-ID: ACES_MOUSE, Q543Z1_MOUSE
UniprotKB: P21836, Q543Z1
UniParc: UPI000000403E
EMBL: X56518, AK046080, AK140404, AK042335, BC046327, AK043748, AF312033
Ensembl: ENSMUSG00000023328
KO: mmu:11423
Nucleutide sequences
EMBL-CDS: CAA39867.1, AAK28816.1, AAH46327.1, BAE24373.1, BAC32595.1, BAC31228.1, BAC31641.1
Ensembl_TRS: ENSMUST00000024099, ENSMUST00000085934
Protein sequencees
Ensembl_PRO: ENSMUSP00000083097, ENSMUSP00000024099
RefSeq: NP_033729.1, XP_036020624.1, NP_001276939.1
Others
UniRef100: UniRef100_P21836
UniRef90: UniRef90_P37136
UniRef50: UniRef50_P37136
UniGene: Mm.255464, Mm.489229
CCDS: CCDS19763.1

全选

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