| Type | Description |
|---|---|
| Definition | KISS1 receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:30:00 | These findings suggest that the previously observed obesity and decreased metabolism in global Kiss1r KOs reflect impaired kisspeptin signaling in non-BAT tissues. | 31914628 |
| 2020-06-27 11:03:00 | Loss of Kiss1r expression is associated with hypogonadal, obese, and metabolically-impaired phenotype. | 31442544 |
| 2019-12-14 11:41:00 | deletion from all cells but GnRH neurons abolishes the effect of kisspeptin on prolactin secretion | 30668693 |
| 2019-03-30 10:08:00 | we demonstrate that in the presence of E2, NKB signaling induces LH release in a kisspeptin-independent manner through the activation of NK3R (NKB receptor) neurons in the posterodorsal medial amygdala (MePD). Importantly, we show that chemogenetic activation of MePD Kiss1 neurons induces LH release, however, the stimulatory action of NKB in this area is Kiss1 neuron-independent. | 30565563 |
| 2019-02-16 10:48:00 | These lines of evidence suggest that downregulation of Ob-R and kisspeptin/GPR54 in the murine hypothalamus may contribute to male hypogonadism caused by high-fat diet-induced obesity. | 29948931 |
| Type | IDs |
|---|---|
| Synonymous | Gpr54, KiSS-1, kiSS-1R |
| Gene |
UniProtKB-ID:
KISSR_MOUSE,
C5H7S2_MOUSE,
B2CP06_MOUSE
UniprotKB:
Q91V45,
C5H7S2,
B2CP06
UniParc:
UPI00000260DF,
UPI0001A90386
EMBL:
GU075727,
EU879091,
EU532437,
AF343726,
AK039628,
AY044228,
AC151846,
BC016531
Ensembl:
ENSMUSG00000035773
KO:
mmu:114229
|
| Nucleutide sequences |
EMBL-CDS:
AAH16531.1,
BAC30404.1,
AAK95814.1,
AAK83236.1,
ACY56024.1,
ACI46599.1,
ACB56626.1
Ensembl_TRS:
ENSMUST00000045529,
ENSMUST00000219745
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040516,
ENSMUSP00000151936
RefSeq:
XP_006513142.1,
NP_001345939.1,
NP_444474.1,
XP_006513140.1,
XP_006513139.1
|
| Others |
UniRef100:
UniRef100_C5H7S2,
UniRef100_Q91V45
UniRef90:
UniRef90_Q924U1,
UniRef90_C5H7S2
UniRef50:
UniRef50_Q969F8,
UniRef50_A0A2K5D9C2
UniGene:
Mm.191035
CCDS:
CCDS23998.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员