| Type | Description |
|---|---|
| Definition | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Angiotensin I Infusion Reveals Differential Effects of Angiotensin-Converting Enzyme in Aortic Resident Cells on Aneurysm Formation. | 32238693 |
| 2020-09-19 16:30:00 | ACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP. | 31871049 |
| 2019-12-14 11:41:00 | Natural angiotensin converting enzyme (ACE) C-domain-specific substrates are not well-described, and we propose that the peptide(s) responsible for the striking ACE-mediated enhancement of myeloid function are substrates/products of the ACE C-domain | 30670595 |
| 2019-09-21 11:39:00 | ACE's two catalytically independent domains, the N- and C-domains, can process a variety of substrates other than angiotensin I. In models lacking either a functional ACE N-domain (NKO) or C-domain (CKO), in response to a saline challenge, diabetic NKO mice excreted 32% more urinary sodium compared with diabetic wild-type or CKO mice. | 30185469 |
| 2019-06-01 10:17:00 | We show sex dimorphism in the severity of diabetes- and ANGII-related renal lesions, and demonstrate that ACE2- and ACE-related compensatory mechanisms are sex-specific. Supporting our previous findings, the modulation and ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy progression was more evident in males. | 29884907 |
| Type | IDs |
|---|---|
| Synonymous | AW208573, CD143 |
| Gene |
UniProtKB-ID:
ACE_MOUSE,
Q3TU20_MOUSE
UniprotKB:
P09470,
Q3TU20
UniParc:
UPI0000006C3A,
UPI0000020BD5
EMBL:
BC040404,
J03940,
AK161020,
J04946,
BC110362,
J04947,
M61094,
M55333
Ensembl:
ENSMUSG00000020681
KO:
mmu:11421
|
| Nucleutide sequences |
EMBL-CDS:
AAA37148.1,
AAH40404.1,
AAA37150.1,
AAA37146.1,
AAA37149.1,
AAA37147.1,
BAE36151.1,
AAI10363.1
Ensembl_TRS:
ENSMUST00000001964,
ENSMUST00000001963
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001964,
ENSMUSP00000001963
RefSeq:
NP_997507.1,
NP_001268748.1,
NP_033728.1
|
| Others |
UniRef100:
UniRef100_P09470
UniRef90:
UniRef90_P47820
UniRef50:
UniRef50_P12821
UniGene:
Mm.754
CCDS:
CCDS25543.1,
CCDS25544.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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