Sh2b2 - SH2B adaptor protein 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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114203 Sh2b2

基因描述

Type	Description
Definition	SH2B adaptor protein 2

研究结论

Date	Results	Publications
2010-01-21 00:00:00	APS was identified as a novel substrate for protein kinase B/Akt.	16141217

名称对应

Type	IDs
Synonymous	Aps
Gene	UniProtKB-ID: SH2B2_RAT UniprotKB: Q9Z200 UniParc: UPI00000E5F31 EMBL: AF095576 Ensembl: ENSRNOG00000001425 KO: rno:114203
Nucleutide sequences	EMBL-CDS: AAC64408.1 Ensembl_TRS: ENSRNOT00000001935
Protein sequencees	Ensembl_PRO: ENSRNOP00000001935 RefSeq: XP_017453726.1, XP_017453727.1, XP_017453728.1, XP_008767334.1, XP_008767335.1, NP_446121.1
Others	UniRef100: UniRef100_Q9Z200 UniRef90: UniRef90_Q9JID9 UniRef50: UniRef50_Q9JID9 UniGene: Rn.163202

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18492766	Wdnm1-like, a new adipokine with a role in MMP-2 activation. Am J Physiol Endocrinol Metab Yu Wu , Cynthia M Smas	2008-07-01	-
17347799	Regulation of insulin receptor function. Cell. Mol. Life Sci. J F Youngren	2007-04-01	Sh2b2, Ins1, Ins2, Prkca, Prkcg, Ptpn1, Insr, Prkcb, Stat5b, Ptprf, Grb10, Grb14, Shc1, Prkcq, Enpp1
16824542	Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS. J. Mol. Biol. Junjie Hu , Stevan R Hubbard	2006-08-04	Jak2, Sh2b1, Sh2b2
16141217	Cross-talk between the two divergent insulin signaling pathways is revealed by the protein kinase B (Akt)-mediated phosphorylation of adapter protein APS on serine 588. J Biol Chem Kostas D Katsanakis , Tahir S Pillay	2005-11-11	-
15946664	The interaction between the adaptor protein APS and Enigma is involved in actin organisation. Exp. Cell Res. Romain BarrÃ¨s , Teresa Gonzalez , Yannick Le Marchand-Brustel , Jean-FranÃ§ois Tanti	2005-08-15	Sh2b2, Pdlim5, Pdlim7, SH2B2, PDLIM7
15231829	Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex. J Biol Chem Andrew Wilcox , Kostas D Katsanakis , Farheen Bheda , T S Pillay	2004-09-10	-
15031295	Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling. J Biol Chem Mee-Young Ahn , Kostas D Katsanakis , Farheen Bheda , Tahir S Pillay	2004-05-14	-
14993264	Increased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domains. Mol Cell Biol Masanori Iseki , Chiyomi Kubo , Sang-Mo Kwon , Akiko Yamaguchi , Yuki Kataoka , Nobuaki Yoshida , Kiyoshi Takatsu , Satoshi Takaki	2004-03-01	-
14690593	Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol. Cell Junjie Hu , Jun Liu , Rodolfo Ghirlando , Alan R Saltiel , Stevan R Hubbard	2003-12-01	Sh2b2, INSR

研究热度

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