| Type | Description |
|---|---|
| Definition | sialic acid binding Ig like lectin 11 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-15 10:33:00 | The authors demonstrated that the human-specific pathogen Escherichia coli K1 uses its polysialic acid capsule as a molecular mimic to engage Siglec-11 and escape killing. In contrast, engagement of the activating counterpart Siglec-16 increases elimination of bacteria. | 28100677 |
| 2012-05-19 10:25:00 | The results indicate potential roles for Siglec-11 in ovarian physiology and human evolution. | 21467073 |
| 2010-05-10 11:07:00 | Siglec-11 ectopically expressed on murine microglia interacts with PSA on neurons, reduces LPS-induced gene transcription of proinflammatory mediators, impairs phagocytosis and alleviates microglial neurotoxicity. | 20203208 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| 2010-01-21 00:00:00 | cloning and characterization; a recently evolved signaling that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages including brain microglia | 11986327 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SIG11_HUMAN
UniprotKB:
Q96RL6
UniParc:
UPI00018131F5,
UPI00018131F6
EMBL:
AC011452,
AF337818,
AY358135
Ensembl:
ENSG00000161640
KO:
hsa:114132
|
| Nucleutide sequences |
EMBL-CDS:
AAQ88502.1,
AAK72907.1
Gene_ORFName:
UNQ9222/PRO28718
Ensembl_TRS:
ENST00000447370,
ENST00000426971
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000412361,
ENSP00000398891
RefSeq:
NP_001128635.1,
XP_005258534.2,
XP_005258533.2,
NP_443116.2
|
| Others |
UniRef100:
UniRef100_Q96RL6
UniRef90:
UniRef90_Q96RL6
UniRef50:
UniRef50_Q96RL6
UniGene:
Hs.661852
CCDS:
CCDS46150.1,
CCDS12790.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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