| Type | Description |
|---|---|
| Definition | N-acylsphingosine amidohydrolase 2 |
| Date | Results | Publications |
|---|---|---|
| 2012-01-28 12:00:00 | Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA. | 21613224 |
| 2011-10-01 12:08:00 | mucin box and signal/anchor sequence of a rat neutral ceramidase recruit bacterial sphingomyelinase to the plasma membranes of mammalian cells | 21597176 |
| 2010-01-21 00:00:00 | The presence of bile salts is important for maintaining high intraluminal levels of Alk-SMase and N-CDase, two key enzymes for hydrolysis of sphingomyelin in the gut. | 17204455 |
| 2010-01-21 00:00:00 | insights into the actions of Pseudomonas aeruginosa CDases and eukaryotic neutral CDases as an exotoxin and mediators of sphingolipid signaling are also revealed, respectively | 19088069 |
| 2010-01-21 00:00:00 | Data show that conserved hydrophobic amino acid residues in the COOH-terminal tail are indispensable for the correct folding and localization, and enzyme activity of neutral ceramidase. | 15123644 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ASAH2_RAT
UniprotKB:
Q91XT9
UniParc:
UPI00000E5D59
EMBL:
AB057433
Ensembl:
ENSRNOG00000012196
KO:
rno:114104
|
| Nucleutide sequences |
EMBL-CDS:
BAB62033.1
Ensembl_TRS:
ENSRNOT00000077135,
ENSRNOT00000016688
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000073116,
ENSRNOP00000016688
RefSeq:
XP_008758542.1,
NP_446098.1,
XP_017444138.1,
XP_006231325.1,
XP_017444137.1,
XP_006231332.1,
XP_017444136.1,
XP_017444139.1,
XP_017444135.1,
XP_006231330.1,
XP_017444140.1
|
| Others |
UniRef100:
UniRef100_Q91XT9
UniRef90:
UniRef90_Q91XT9
UniRef50:
UniRef50_Q9NR71
UniGene:
Rn.156958
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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