| Type | Description |
|---|---|
| Definition | cholinergic receptor nicotinic beta 2 subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:19:00 | Identification of the initial steps in signal transduction in the alpha4beta2 nicotinic receptor has been reported. | 31130483 |
| 2019-08-10 11:52:00 | The fifth subunit in the (alpha4beta2)2 beta2 receptor isoform modulates maximal ACh responses. This effect appears to be driven by a modulatory, and asymmetric, association with the alpha4(+)/beta2(-) agonist sites. | 28600847 |
| 2018-10-20 11:27:00 | cryoelectron microscopy and the structural principles of distinct assemblies of the human alpha4beta2 nicotinic receptor | 29720657 |
| 2018-02-03 10:44:00 | the mechanism of interaction between [Upsilon4E]GID and the agonist binding pockets of the alpha4beta2 and the halpha7 receptors, and to estimate their relative binding affinities, was investigated. | 27721068 |
| 2018-01-06 10:26:00 | Reactive oxygen species, generated by 6-hydroxydopamine (6-OHDA), could cause the current rundown in alpha4beta2 nAChRs, which may play a role in Parkinson disease. | 27445102 |
| Type | IDs |
|---|---|
| Synonymous | EFNL3, nAChRB2 |
| Gene |
UniProtKB-ID:
ACHB2_HUMAN,
Q5SXY3_HUMAN
UniprotKB:
P17787,
Q5SXY3
UniParc:
UPI000012526E
EMBL:
BC075040,
AJ001936,
AF077186,
Y08415,
AJ001937,
AJ001939,
BC075041,
U62437,
AJ001935,
AK313470,
AJ001938,
CH471121,
X53179
Ensembl:
ENSG00000160716
KO:
hsa:1141
|
| Nucleutide sequences |
EMBL-CDS:
AAD45422.1,
CAA05108.1,
CAA69692.1,
AAB40115.1,
CAA37320.1,
AAH75041.1,
AAH75040.1,
BAG36255.1,
EAW53192.1
Gene_ORFName:
hCG_18732
Ensembl_TRS:
ENST00000368476
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357461
RefSeq:
XP_016855669.1,
NP_000739.1
|
| Others |
UniRef100:
UniRef100_P17787
UniRef90:
UniRef90_Q9ERK7
UniRef50:
UniRef50_Q9ERK7
UniGene:
Hs.2306
CCDS:
CCDS1070.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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