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114088 TRIM9

114088

TRIM9

tripartite motif containing 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition tripartite motif containing 9

研究结论

Date Results Publications
2020-09-19 16:28:00 TRIM9 overexpression promotes uterine leiomyoma cell proliferation and inhibits cell apoptosis via NF-kappaB signaling pathway. 32679146
2020-06-27 10:32:00 Findings reveal that TRIM9 is essential for resolving NF-kappaB-dependent neuroinflammation to promote recovery and repair after brain injury. 30970257
2019-09-21 10:14:00 TRIM9s promotes the K63-linked ubiquitination of MKK6 at Lys82, thus inhibiting the degradative K48-linked ubiquitination of MKK6 at the same lysine. MKK6 could also stabilize TRIM9s by promoting the phosphorylation of TRIM9s at Ser76/80 via p38, thereby blocking the ubiquitin-proteasome pathway. 29669288
2017-12-09 11:58:00 TRIM9s undergoes Lys-63-linked auto-polyubiquitination and serves as a platform to bridge GSK3beta to TBK1, leading to the activation of IRF3 signaling. 26915459
2017-11-18 12:38:00 Authors demonstrate that tripartite motif protein 9 (TRIM9)-dependent ubiquitination of DCC blocks the interaction with and phosphorylation of FAK. 28701345

名称对应

Type IDs
Synonymous RNF91, SPRING
Gene
UniProtKB-ID: TRIM9_HUMAN
UniprotKB: Q9C026
UniParc: UPI00000726FE, UPI00001B57AD, UPI000006D630
EMBL: BC013414, AK055388, AF220036, AF220037, AF220038, CH471078, D87458, BC063872
Ensembl: ENSG00000100505
KO: hsa:114088
Nucleutide sequences
EMBL-CDS: EAW65684.1, EAW65682.1, AAG53490.1, EAW65680.1, AAG53492.1, BAB70913.1, AAH63872.1, BAA13398.2, AAG53491.1, AAH13414.1, EAW65681.1
Ensembl_TRS: ENST00000338969, ENST00000298355, ENST00000360392
Protein sequencees
Ensembl_PRO: ENSP00000342970, ENSP00000298355, ENSP00000353561
RefSeq: XP_016876434.1, NP_443210.1, NP_001374300.1, XP_016876435.1, XP_005267359.1, NP_001374302.1, NP_001374307.1, NP_001374297.1, NP_001374296.1, XP_016876438.1, XP_016876433.1, NP_001374303.1, NP_001374291.1, NP_001374298.1, NP_001374294.1, XP_016876437.1, XP_016876432.1, NP_001374304.1, NP_001374308.1, NP_001374309.1, NP_001374292.1, NP_001374299.1, XP_005267358.1, NP_001374301.1, NP_001374306.1, XP_016876439.1, NP_001374305.1, NP_001374293.1, XP_011534691.1, NP_001374290.1, XP_016876436.1, XP_006720081.1, NP_055978.4, NP_001374295.1, NP_001374289.1
Others
UniRef100: UniRef100_Q9C026
UniRef90: UniRef90_Q9C026
UniRef50: UniRef50_Q9C026
UniGene: Hs.654750
CCDS: CCDS9703.1, CCDS45105.1

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