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114034 TOE1

114034

TOE1

target of EGR1, exonuclease

protein-coding

Homo sapiens

基因描述

Type Description
Definition target of EGR1, exonuclease

研究结论

Date Results Publications
2019-09-21 10:14:00 PARN and TOE1 do not modulate the length of mRNA poly(A) tails. Rather, they promote the maturation of nuclear small non-coding RNAs (ncRNAs). PARN and TOE1 act redundantly on some ncRNAs, most prominently small Cajal body-specific RNAs (scaRNAs). 29669292
2019-08-31 13:10:00 Our study highlights a mechanistic link between TOE1 mutation, improper hTR processing and telomere dysfunction in diseases such as Pontocerebella Hypoplasia Type 7 . 30371886
2017-09-09 12:11:00 Human cells with reduced levels of TOE1 accumulated 3'-end-extended pre-snRNA. 28092684
2015-11-21 10:22:00 Antiviral potency of TOE1 and its cell-penetrating capability have been identified to lie within a 35-amino-acid region containing the nuclear localization sequence 26056259
2010-01-21 00:00:00 TOE1 has a role in the growth inhibitory activity of Egr1 12562764

名称对应

Type IDs
Synonymous PCH7, hCaf1z
Gene
UniProtKB-ID: TOE1_HUMAN
UniprotKB: Q96GM8
UniParc: UPI00017A6BCE, UPI00000382DE
EMBL: BC009364, AK293704, AY169960, CR457320, AL359540, AK024011
Ensembl: ENSG00000132773
KO: hsa:114034
Nucleutide sequences
EMBL-CDS: AAN75441.1, BAG57137.1, CAG33601.1, BAB14774.1, AAH09364.1
Ensembl_TRS: ENST00000372090
Protein sequencees
Ensembl_PRO: ENSP00000361162
RefSeq: XP_024308605.1, XP_005270470.1, XP_005270469.1, XP_011538871.1, NP_079353.3
Others
UniRef100: UniRef100_Q96GM8
UniRef90: UniRef90_Q96GM8
UniRef50: UniRef50_Q96GM8
UniGene: Hs.525091
CCDS: CCDS521.1

全选

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研究热度

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