| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory (inhibitor) subunit 14A |
| Date | Results | Publications |
|---|---|---|
| 2018-07-28 11:49:00 | an impairment of the rapid CPI-17 signaling pathway mediating alpha1A-adrenoceptor activation is a cause of hypo-responsiveness of splanchnic resistance arteries, as an end organ of orthostatic blood pressure reflex, in the orthostatic hypotension model rats | 28717991 |
| 2015-05-30 12:14:00 | Emodin attenuates tonic tension through the blockade of and CPI-17-mediated MLC-phosphatase inhibition. | 24909118 |
| 2015-05-23 11:28:00 | Rac1 coordinates with RhoA to increase myosin light chain (MLC) phosphorylation by inactivation of CPI-17/MYPT1 phosphatase, which decreases MLC phosphatase activity thus promoting MLC phosphorylation and cell contraction | 25502873 |
| 2013-07-06 10:38:00 | Nuclear accumulation of CPI-17 is detected in proliferating vascular smooth muscle cell cultures and in neointima cells of a vascular injury model. | 23541585 |
| 2012-09-15 10:16:00 | results suggest that myocardin-independent Sp1/Sp3 pathways regulate the CPI-17 transcription through multiple kinases, such as ERK1/2, p38, JNK, and ROCK in response to environmental changes | 22538237 |
| Type | IDs |
|---|---|
| Synonymous | Cpi17 |
| Gene |
UniProtKB-ID:
PP14A_RAT
UniprotKB:
Q99MC0
UniParc:
UPI00000E6FB2
EMBL:
AY050673,
AF352572
Ensembl:
ENSRNOG00000020676
KO:
rno:114004
|
| Nucleutide sequences |
EMBL-CDS:
AAL25831.1,
AAK35213.1
Ensembl_TRS:
ENSRNOT00000028070
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000028070
RefSeq:
NP_569087.1,
XP_017444133.1
|
| Others |
UniRef100:
UniRef100_Q99MC0
UniRef90:
UniRef90_Q99MC0
UniRef50:
UniRef50_O18734
UniGene:
Rn.73852
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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