| Type | Description |
|---|---|
| Definition | cholinergic receptor nicotinic beta 1 subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-11-11 13:41:00 | Study traced the cause of congenital myasthenia syndrome in unrelated patients with dominant missense mutations in the M2 domain of AChR. A valine residue is replaced by a smaller alanine either in the epsilon subunit or an equivalent position in the beta one. Also, each valine in the valine ring was found to contribute to channel kinetics equally, and the valine ring has bee optimized during evolution to govern channe... | 27375219 |
| 2017-04-01 12:15:00 | This study reports on the presence of the CHRNB1 at the cellular level in human skeletal muscle and placenta and that mRNA expression mirrors that of protein within cell types. | 28153524 |
| 2014-03-22 10:06:00 | These findings identify novel Golgi retention signals in the beta and delta subunit loops that regulate surface trafficking of assembled AChR and may help prevent surface expression of unassembled subunits. | 24240098 |
| 2013-01-26 11:42:00 | Single nucleotide polymorphisms , rs55633891 (alpha9, C>T) and rs17856697 (beta1, A>G), did not exhibit a significant trend to be associated with cervical lesions. | 22406075 |
| 2010-12-05 22:09:00 | Observational study of gene-disease association. (HuGE Navigator) | 20734064 |
| Type | IDs |
|---|---|
| Synonymous | ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS |
| Gene |
UniProtKB-ID:
ACHB_HUMAN
UniprotKB:
P11230
UniParc:
UPI0001914FCA,
UPI0000125257
EMBL:
BC011371,
BC023553,
X14830,
AK298938,
AC113189
Ensembl:
ENSG00000170175,
ENSG00000283946
KO:
hsa:1140
|
| Nucleutide sequences |
EMBL-CDS:
BAH12907.1,
AAH11371.1,
CAA32939.1,
AAH23553.1
Ensembl_TRS:
ENST00000639692,
ENST00000306071,
ENST00000536404,
ENST00000639993
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304290,
ENSP00000492221,
ENSP00000439209,
ENSP00000491113
RefSeq:
NP_000738.2
|
| Others |
UniRef100:
UniRef100_P11230
UniRef90:
UniRef90_P11230
UniRef50:
UniRef50_P11230
UniGene:
Hs.330386
CCDS:
CCDS11106.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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