| Type | Description |
|---|---|
| Definition | acyl-Coenzyme A dehydrogenase, very long chain |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:01:00 | and VLCAD-/- mice showed strong sex-dependent differences in basal metabolism and expression of proteins involved in the distinct metabolic pathways, even more prominent after treatment with octanoate. | 31394165 |
| 2019-04-27 11:39:00 | our results demonstrate that infection as a stress produces perturbations in metabolism in Acadvl(-/-) that differ greatly from WT infected and Acadvl(-/-) pair-fed controls. This model system will be useful for studying the effects of infection on tissue metabolism as well as evaluating interventions aimed at modulating the effects of metabolic decompensation. | 30031688 |
| 2019-01-05 10:23:00 | the MCL-1 BH3 interaction with VLCAD revealed a separable, gain-of-function role for MCL-1 in the regulation of lipid metabolism. | 29499131 |
| 2017-08-26 12:22:00 | Triheptanoin was not able to prevent the development of systolic dysfunction in VLCAD(-/-) mice despite an upregulation of cardiac glucose oxidation. Strikingly, the anaplerotic effects of triheptanoin were restricted to the liver. | 27884962 |
| 2016-04-23 10:06:00 | observed strong upregulation of peroxisomal beta-oxidation in VLCAD(-/-) mice | 26284828 |
| Type | IDs |
|---|---|
| Synonymous | vlcad |
| Gene |
UniProtKB-ID:
ACADV_MOUSE
UniprotKB:
P50544
UniParc:
UPI0000001A12
EMBL:
Y11770,
AF017176,
Z71189,
BC026559,
U41497
Ensembl:
ENSMUSG00000018574
KO:
mmu:11370
|
| Nucleutide sequences |
EMBL-CDS:
CAA72435.1,
AAC31642.1,
AAA85185.1,
CAA94919.2,
AAH26559.1
Ensembl_TRS:
ENSMUST00000102574
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099634
RefSeq:
NP_059062.1
|
| Others |
UniRef100:
UniRef100_P50544
UniRef90:
UniRef90_P50544
UniRef50:
UniRef50_P50544
UniGene:
Mm.18630
CCDS:
CCDS24931.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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