| Type | Description |
|---|---|
| Definition | helicase, POLQ like |
| Date | Results | Publications |
|---|---|---|
| 2018-07-14 10:05:00 | HELQ plays an important role in regulating the expression of DNA repair proteins NER pathway which, in turn, contributes to cellular response to cisplatin and patients' response to platinum-based chemotherapy. | 29572031 |
| 2017-12-30 11:32:00 | WHD domain may contribute to ssDNA translocation, resulting in DNA helicase activity or in removal of other DNA bound proteins by "reeling" ssDNA. | 28738244 |
| 2017-03-25 12:18:00 | HELQ regulates the CHK1-RAD51 signaling pathway in osteosarcoma cells. | 28000895 |
| 2016-10-08 12:24:00 | Our results indicate that HELQ is not a major breast and ovarian cancer susceptibility gene in the Finnish population | 26351136 |
| 2016-08-06 10:44:00 | No mutation was identified. Our study indicates for the first time that mutations in the coding sequence of the HELQ gene may not be responsible for premature ovarian failure in Chinese Han population. | 26190809 |
| Type | IDs |
|---|---|
| Synonymous | HEL308 |
| Gene |
UniProtKB-ID:
HELQ_HUMAN
UniprotKB:
Q8TDG4
UniParc:
UPI0001AE7461,
UPI0001D14755,
UPI000013E25F,
UPI0001D14754
EMBL:
AC096768,
AL512702,
AF436845,
BC095473,
BC015428,
AK128665
Ensembl:
ENSG00000163312
KO:
hsa:113510
|
| Nucleutide sequences |
EMBL-CDS:
BAC87559.1,
AAH95473.1,
CAH56359.1,
AAH15428.1,
AAL85274.1
Ensembl_TRS:
ENST00000295488
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295488
RefSeq:
NP_001284686.1,
NP_001284684.2,
NP_598375.3,
NP_001284687.2,
NP_001284685.1,
NP_001284688.2
|
| Others |
UniRef100:
UniRef100_Q8TDG4
UniRef90:
UniRef90_Q8TDG4
UniRef50:
UniRef50_Q8TDG4
UniGene:
Hs.480101
CCDS:
CCDS3603.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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