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11346 SYNPO

11346

SYNPO

synaptopodin

protein-coding

Homo sapiens

基因描述

Type Description
Definition synaptopodin

研究结论

Date Results Publications
2020-08-22 15:26:00 Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin. 32398370
2020-06-13 11:55:00 We show that recombinant human KIBRA WW2 domain is primarily disordered, binds SYNPO with relatively weak affinity and remains largely disordered in the complex. 31597702
2018-05-12 10:22:00 The postsynaptic protein, synaptopodin (SYNPO) was significantly down-regulated in both dementia with Lewy bodies and Parkinson's disease dementia subgroups, suggesting a defective synaptic transmission in the demented patients. 28800743
2017-08-12 11:52:00 Urine synaptopodin is associated with serum creatinine elevation in the patients with glomerulonephritis including diabetic kidney disease regardless of urine albumin excretion. We suggest that the urine synaptopodin level can predict glomerular damage independently of the urine albumin excretion. 27604800
2017-01-14 10:36:00 SYNPO variants are involved in AMPA receptor trafficking and neuronal plasticity, which are associated with cognitive impairment and schizophrenia susceptibility. 26405221

名称对应

Type IDs
Gene
UniProtKB-ID: SYNPO_HUMAN
UniprotKB: Q8N3V7
UniParc: UPI00000701DC, UPI000013F943, UPI0000376AC3
EMBL: AF499136, AL831818, AB028952, BC146665, AK290178, CH471062, AF499137, AK127049, Y11072, BC142683
Ensembl: ENSG00000171992
KO: hsa:11346
Nucleutide sequences
EMBL-CDS: AAQ07402.1, EAW61715.1, AAI42684.1, CAA71955.1, CAD38532.1, AAI46666.1, BAF82867.1, EAW61716.1, AAQ07403.1, BAA82981.2
Ensembl_TRS: ENST00000519664, ENST00000522122, ENST00000307662, ENST00000394243
Protein sequencees
Ensembl_PRO: ENSP00000302139, ENSP00000377789, ENSP00000428378, ENSP00000429268
RefSeq: NP_001159680.1, NP_001103444.1, XP_005268428.1, XP_011535854.1, NP_009217.3, XP_005268427.1, XP_016864497.1, NP_001159681.1, XP_006714818.1, XP_024310119.1, XP_016864496.1
Others
UniRef100: UniRef100_Q8N3V7
UniRef90: UniRef90_Q8N3V7
UniRef50: UniRef50_Q8CC35
UniGene: Hs.435228
CCDS: CCDS54937.1, CCDS54938.1, CCDS4308.1

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