| Type | Description |
|---|---|
| Definition | cholinergic receptor nicotinic alpha 1 subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:13:00 | Point Mutations of Nicotinic Receptor alpha1 Subunit Reveal New Molecular Features of G153S Slow-Channel Myasthenia. | 33652901 |
| 2020-07-11 10:49:00 | Serum AChR alpha1 subunit protein concentrations were higher in patients with ant-AChR antibody-positive myasthenia gravis than those in controls. | 31855720 |
| 2018-12-22 10:50:00 | In our analysis, we found one pair of SNPs in CHRNA1 and CHRNA7, plus one pair of SNPs in CHRNA2 and CHRNA3 reached corrected significance in tests for GxG interaction. Our study suggested evidence of interactions between CHRNs in controlling the risk of NSCL/P. | 29688589 |
| 2017-08-19 12:38:00 | Data suggest that the mutations made the cholinergic receptor nicotinic alpha 1 subunit channel (CHRNA1) resistant to the antagonists, not by impairing antagonist binding, but rather by producing a gain-of-function phenotype, e.g. increased agonist sensitivity. | 27649498 |
| 2017-02-18 10:57:00 | Study indicated that nicotinic acetylcholine receptor alpha 1-subunit peptides may act as receptor decoy molecules and inhibit the binding of virus to the native host cell receptors and hence may reduce viral infection. | 26656837 |
| Type | IDs |
|---|---|
| Synonymous | ACHRA, ACHRD, CHRNA, CMS1A, CMS1B, CMS2A, FCCMS, SCCMS |
| Gene |
UniProtKB-ID:
ACHA_HUMAN,
Q53SH4_HUMAN
UniprotKB:
P02708,
Q53SH4
UniParc:
UPI000002A339,
UPI000012524E
EMBL:
X02508,
X17104,
X02502,
AK315312,
X02506,
AK299445,
Y00762,
X02507,
CH471058,
X02503,
S77094,
X02504,
X02505,
AC018890,
X70108,
AK291338
Ensembl:
ENSG00000138435
KO:
hsa:1134
|
| Nucleutide sequences |
EMBL-CDS:
EAX11125.1,
CAA26344.1,
CAA34960.1,
AAD14247.1,
BAG61418.1,
CAA49705.1,
CAA68731.1,
EAX11127.1,
BAG37716.1,
EAX11128.1,
EAX11124.1,
AAY14687.1,
BAF84027.1
Gene_ORFName:
hCG_1811440
Ensembl_TRS:
ENST00000348749,
ENST00000261007
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261008,
ENSP00000261007
RefSeq:
XP_016858745.1,
XP_016858746.1,
NP_000070.1,
NP_001034612.1
|
| Others |
UniRef100:
UniRef100_P02708,
UniRef100_Q53SH4
UniRef90:
UniRef90_P54249,
UniRef90_P02708
UniRef50:
UniRef50_P02708
UniGene:
Hs.434479
CCDS:
CCDS33331.1,
CCDS2261.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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