| Type | Description |
|---|---|
| Definition | U2 small nuclear RNA auxiliary factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. | 33020180 |
| 2021-02-27 13:45:00 | Influenza virus natural sequence heterogeneity in segment 8 affects interactions with cellular RNA-binding proteins and splicing efficiency. | 32829114 |
| 2020-07-18 11:38:00 | intrinsically disordered linker region connecting the two RNA recognition motif domains of U2AF2 mediates autoinhibitory intramolecular interactions to reduce nonproductive binding to weak Py-tract RNAs | 32188783 |
| 2020-05-02 12:38:00 | The splicing factors U2AF65 and CAPERalpha engage multivalent interactions through their low complexity RS domains. The resulting assemblies can bridge the U2snRNP component SF3b155 with repeated polypyrimidine tracts in introns, to promote alternative splicing. | 31271494 |
| 2019-12-07 11:31:00 | Taken together, the present study provides the first evidence that OTUB2 acts as a pivotal driver in non-small cell lung cancer tumorigenesis by stabilizing U2AF2 and activating the AKT/mTOR pathway and the Warburg effect. | 30662561 |
| Type | IDs |
|---|---|
| Synonymous | U2AF65 |
| Gene |
UniProtKB-ID:
U2AF2_HUMAN
UniprotKB:
P26368
UniParc:
UPI000000B2E8,
UPI0000137924
EMBL:
CH471135,
X64044,
BC008740,
BC030574
Ensembl:
ENSG00000063244
KO:
hsa:11338
|
| Nucleutide sequences |
EMBL-CDS:
AAH08740.1,
AAH30574.1,
EAW72404.1,
CAA45409.1
Ensembl_TRS:
ENST00000450554,
ENST00000308924
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000388475,
ENSP00000307863
RefSeq:
XP_006723057.1,
NP_001012496.1,
XP_011524712.1,
NP_009210.1
|
| Others |
UniRef100:
UniRef100_P26368
UniRef90:
UniRef90_P26368
UniRef50:
UniRef50_P26368
UniGene:
Hs.528007
CCDS:
CCDS12933.1,
CCDS46197.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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