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1132 CHRM4

1132

CHRM4

cholinergic receptor muscarinic 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition cholinergic receptor muscarinic 4

研究结论

Date Results Publications
2020-08-22 15:25:00 Group II muscarinic acetylcholine receptors attenuate hepatic injury via Nrf2/ARE pathway. 32234387
2020-06-27 10:38:00 Authors discuss how M4 activity regulates DA release and signaling, the potential sources of ACh that can regulate M4 activity, and the implications of targeting M4 activity for the treatment of the motor symptoms in movement disorders. [Review] 31211471
2017-08-12 10:17:00 the association of the African-specific CHRM4 SNP with cocaine dependence survived correction for multiple testing 27269905
2016-04-16 10:45:00 crystal structures of the M1 and M4 muscarinic receptors bound to the inverse agonist, tiotropium 26958838
2015-08-22 10:30:00 This study demonstrated that CD4+ and CD8+ T cells expressed M2 and M4 muscarinic receptors which density were significantly increased in asthmatic children in comparison with controls. 26025056

名称对应

Type IDs
Synonymous HM4, M4R
Gene
UniProtKB-ID: ACM4_HUMAN
UniprotKB: P08173
UniParc: UPI00001252BB
EMBL: BC137535, AF498918, BC119775, M16405, BC119817, BC095546, CH471064, X15265
Ensembl: ENSG00000180720
KO: hsa:1132
Nucleutide sequences
EMBL-CDS: AAI19776.1, AAI37536.1, AAI19818.1, CAA33336.1, AAA51571.2, AAH95546.1, EAW68004.1, AAM18941.1
Ensembl_TRS: ENST00000433765
Protein sequencees
Ensembl_PRO: ENSP00000409378
RefSeq: NP_000732.2, NP_001353621.1
Others
UniRef100: UniRef100_P08173
UniRef90: UniRef90_P08173
UniRef50: UniRef50_P08485
UniGene: Hs.248100
CCDS: CCDS44581.1

全选

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研究热度

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