| Type | Description |
|---|---|
| Definition | vacuolar protein sorting 45 homolog |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:54:00 | SPI1-induced upregulation of lncRNA SNHG6 promotes non-small cell lung cancer via miR-485-3p/VPS45 axis. | 32590190 |
| 2020-04-18 10:19:00 | The Rab-binding module of FERARI (factors for endosome recycling and Rab interactions) consists of Rab11FIP5 and rabenosyn-5, while the SNARE-interacting module comprises VPS45 and VIPAS39. | 31988382 |
| 2016-10-22 11:57:00 | A homozygous VPS45 p.E238K mutation is associated with severe congenital neutropenia with neurological impairment. | 26358756 |
| 2013-08-31 10:13:00 | we identified a Thr224Asn mutation in the VPS45 gene in infants from consanguineous families who suffered from life-threatening neutropenia. | 23599270 |
| 2013-07-13 12:18:00 | Defective endosomal intracellular protein trafficking due to biallelic mutations in VPS45 underlies a new immunodeficiency syndrome involving impaired neutrophil function. | 23738510 |
| Type | IDs |
|---|---|
| Synonymous | H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A |
| Gene |
UniProtKB-ID:
VPS45_HUMAN,
B7Z5D4_HUMAN,
A0A2R8YE10_HUMAN,
B7Z360_HUMAN
UniprotKB:
Q9NRW7,
B7Z5D4,
A0A2R8YE10,
B7Z360
UniParc:
UPI00000015E6,
UPI0001914F44,
UPI00020654A8,
UPI0001914D6C,
UPI0000204162
EMBL:
AC242988,
AL358073,
U35246,
AK223214,
CH471121,
AK023170,
BC028382,
AK295529,
AJ133421,
AC244033,
AF165513,
AK298786,
BC012932
Ensembl:
ENSG00000136631
KO:
hsa:11311
|
| Nucleutide sequences |
EMBL-CDS:
AAF86643.1,
AAC50931.1,
EAW53584.1,
AAH28382.1,
BAD96934.1,
CAB40417.1,
AAH12932.1,
EAW53585.1,
CAI14265.1,
BAB14443.1,
BAH12870.1,
BAH12096.1
Ensembl_TRS:
ENST00000644510,
ENST00000535106,
ENST00000369128,
ENST00000643970
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358124,
ENSP00000440690,
ENSP00000495563,
ENSP00000495148
RefSeq:
XP_024308559.1,
NP_009190.2,
NP_001266282.1,
NP_001266283.1
|
| Others |
UniRef100:
UniRef100_Q9NRW7,
UniRef100_B7Z5D4,
UniRef100_B7Z360
UniRef90:
UniRef90_Q9NRW7
UniRef50:
UniRef50_Q9NRW7
UniGene:
Hs.443750
CCDS:
CCDS944.1,
CCDS60244.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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