| Type | Description |
|---|---|
| Definition | abl-interactor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:24:00 | CRISPR/CAS9-mediated knockout of Abi1 inhibits p185(Bcr-Abl)-induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways. | 32276588 |
| 2020-04-18 12:26:00 | Wave complex proteins ABI1 and Wave2 have key roles in regulating signals that control epidermal shape and growth by suppressing Wnt-Sox9 signaling. | 30867227 |
| 2019-08-03 10:46:00 | This study shows that bone marrow-specific deletion of Abi1 in a novel mouse model leads to development of an myeloproliferative neoplasms-like phenotype resembling human primary myelofibrosis. Abi1 loss resulted in a significant increase in the activity of the Src family kinases (SFKs), and NF-kappaB signaling. | 30213875 |
| 2016-03-12 10:16:00 | The expression of NESH/Abi-3 caused degradation of endogenous Abi-1, which led to the formation of a NESH/Abi-3-based WAVE2 complex. | 26428302 |
| 2012-01-14 11:12:00 | CDK1-mediated phosphorylation of Abi1 attenuates Bcr-Abl-induced F-actin assembly and tyrosine phosphorylation of WAVE complex during mitosis | 21900237 |
| Type | IDs |
|---|---|
| Synonymous | E3B1, NAP1, Ssh3bp1, abi-1 |
| Gene |
UniProtKB-ID:
ABI1_MOUSE,
B7ZCU0_MOUSE,
B7ZCU4_MOUSE,
Q3TPY5_MOUSE,
Q3TJR5_MOUSE,
B7ZCU2_MOUSE,
Q3TJ64_MOUSE,
B7ZCU3_MOUSE
UniprotKB:
Q8CBW3,
B7ZCU0,
B7ZCU4,
Q3TPY5,
Q3TJR5,
B7ZCU2,
Q3TJ64,
B7ZCU3
UniParc:
UPI0000025987,
UPI00000E9450,
UPI0001889B28,
UPI0000020EEB,
UPI0001889B27,
UPI00005ACA83,
UPI00000E685C,
UPI0001889B26,
UPI0001889B29
EMBL:
AK164040,
AK167328,
CT030013,
U17698,
AL845257,
AK151026,
AY033645,
AK152184,
AF420251,
AK034476,
AK152061,
AK153130,
AK167568,
BC004657,
AK167744
Ensembl:
ENSMUSG00000058835
KO:
mmu:11308
|
| Nucleutide sequences |
EMBL-CDS:
BAE30917.1,
BAE31015.1,
BAE30044.1,
BAC28722.1,
AAK59381.1,
AAH04657.1,
AAB00373.1,
AAL16036.1,
BAE31743.1,
BAE39781.1,
BAE37600.1,
BAE39430.1,
BAE39631.1
Ensembl_TRS:
ENSMUST00000149719,
ENSMUST00000126112,
ENSMUST00000123948,
ENSMUST00000140164,
ENSMUST00000114544,
ENSMUST00000091394,
ENSMUST00000093171,
ENSMUST00000153931,
ENSMUST00000078977
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000120462,
ENSMUSP00000117335,
ENSMUSP00000120621,
ENSMUSP00000110191,
ENSMUSP00000118491,
ENSMUSP00000088957,
ENSMUSP00000090860,
ENSMUSP00000120769,
ENSMUSP00000077997
RefSeq:
NP_031406.2,
NP_001070661.1,
NP_001070660.1,
NP_001364440.1,
NP_001364441.1,
NP_001364442.1,
NP_001317972.1,
NP_666106.1,
NP_001317973.1,
NP_001070658.1,
XP_006497682.1,
NP_001364439.1,
NP_001317974.1
|
| Others |
UniRef100:
UniRef100_Q3TJR5,
UniRef100_Q3TJ64,
UniRef100_Q8CBW3,
UniRef100_B7ZCU4,
UniRef100_B7ZCU2,
UniRef100_B7ZCU0,
UniRef100_B7ZCU3,
UniRef100_Q3TPY5
UniRef90:
UniRef90_F1RTW7,
UniRef90_Q3UAH6,
UniRef90_Q9QZM5,
UniRef90_B7ZCU2,
UniRef90_Q8CBW3,
UniRef90_B7ZCU0
UniRef50:
UniRef50_G3WCF2,
UniRef50_U3JXK7,
UniRef50_Q8IZP0,
UniRef50_A0A6I8SLM4,
UniRef50_Q9QZM5
UniGene:
Mm.205647,
Mm.249752
CCDS:
CCDS38060.1,
CCDS38061.1,
CCDS38059.1,
CCDS50513.1,
CCDS38058.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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