| Type | Description |
|---|---|
| Definition | ATP-binding cassette, sub-family A (ABC1), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-08-06 11:59:00 | Study suggests that ABCA2 modulation of sphingolipid metabolism activates a signaling pathway that regulates amyloid precursor protein transcription | 26510981 |
| 2014-02-22 10:47:00 | control of ABCA2 expression level may be a key locus of regulation for esterification of plasma membrane-derived cholesterol through modulation of sphingolipid metabolism. | 24201375 |
| 2013-02-02 11:25:00 | Data from knockout mice suggest that Abca2 functions in penile erection; Abca2 knockout mice are more susceptible to estrogen-induced convulsions than wildtype mice; Abca2 appears to be involved in biotransformation of therapeutic estrogens. | 22898081 |
| 2013-01-05 10:23:00 | Lack of ABCA2 generates abnormalities in intracellular lipid distribution/trafficking in macrophages, increasing susceptibility to apoptosis in response to oxidized lipids and reduced atherosclerotic lesion development in LDL receptor knockout mice. | 22748276 |
| 2012-03-31 10:05:00 | The ATP-binding cassette transporter-2 (ABCA2) is a key regulator of cholesterol homeostasis and low-density lipoprotein receptor metabolism in neuronal cells. | 21810484 |
| Type | IDs |
|---|---|
| Synonymous | AI413825, Abc2, D2H0S1474E, mKIAA1062 |
| Gene |
UniProtKB-ID:
A2AJ26_MOUSE
UniprotKB:
A2AJ26
UniParc:
UPI000019639C
EMBL:
AL732557
Ensembl:
ENSMUSG00000026944
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000102919
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099983
RefSeq:
XP_036013490.1,
XP_006497679.1,
XP_030102574.1,
XP_006497678.1,
NP_001355553.1,
XP_006497677.1,
XP_006497674.1,
XP_006497673.1,
XP_030102587.1,
XP_006497672.1,
NP_031405.2,
XP_036013494.1
|
| Others |
UniRef100:
UniRef100_A2AJ26
UniRef90:
UniRef90_A2AJ26
UniRef50:
UniRef50_P41234
UniGene:
Mm.2210
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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