| Type | Description |
|---|---|
| Definition | sodium voltage-gated channel alpha subunit 11 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:58:00 | A 49-residue sequence motif in the C terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane. | 31822564 |
| 2020-05-09 11:24:00 | Findings suggest that higher PBMC SCN11A expression levels may be associated with certain behavioral bipolar disorder (BD) sub-phenotypes, including lack of alcohol dependence and psychosis, among BD patients. | 31498915 |
| 2019-12-14 10:27:00 | The frequency of (potentially) pathogenic variants was 5.1% (n=58/1139) for SCN9A, 3.7% (n=42/1139) for SCN10A and 2.9% (n=33/1139) for SCN11A in pure small fibre neuropathy. | 30554136 |
| 2019-09-21 11:27:00 | data suggest an important contribution of NaV1.9 to itch signaling. | 30395542 |
| 2019-06-01 10:15:00 | A total of 11 mutations in SCN11A: p.R222H in seven families, and p.R225C, p.F814C, p.F1146S, or p.V1184A, in independent families. A founder mutation, SCN11A p.R222H was confirmed to be frequently observed in patients with Familial episodic limb pain in Japan. And identification of two novel missense variants of SCN11A, p.F814C and p.F1146S. | 30557356 |
| Type | IDs |
|---|---|
| Synonymous | FEPS3, HSAN7, NAV1.9, NaN, PN5, SCN12A, SNS-2 |
| Gene |
UniProtKB-ID:
SCNBA_HUMAN
UniprotKB:
Q9UI33
UniParc:
UPI000006CCD7,
UPI0000209BDE,
UPI0000ED8FEE
EMBL:
AJ417790,
AF150882,
AC116038,
AY686224,
AF109737,
AF188679
Ensembl:
ENSG00000168356
KO:
hsa:11280
|
| Nucleutide sequences |
EMBL-CDS:
AAT95434.1,
CAD10507.1,
AAF24976.1,
AAF17480.1,
AAF24980.1
Ensembl_TRS:
ENST00000302328,
ENST00000444237,
ENST00000668754,
ENST00000456224
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000408028,
ENSP00000499569,
ENSP00000416757,
ENSP00000307599
RefSeq:
XP_016861140.1,
NP_054858.2,
XP_011531623.1,
XP_016861139.1,
XP_016861136.1,
XP_016861141.1,
NP_001336182.1,
XP_016861142.1,
XP_016861137.1
|
| Others |
UniRef100:
UniRef100_Q9UI33
UniRef90:
UniRef90_Q9UI33
UniRef50:
UniRef50_Q9UI33
UniGene:
Hs.591657
CCDS:
CCDS33737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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