| Type | Description |
|---|---|
| Definition | cholinergic receptor muscarinic 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:12:00 | Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis. | 32205868 |
| 2020-11-21 13:31:00 | Pharmacogenetics of tardive dyskinesia in schizophrenia: The role of CHRM1 and CHRM2 muscarinic receptors. | 30623717 |
| 2019-10-19 12:12:00 | the selective CHRM1 antagonist pirenzepine inhibited PC-3, LNCaP, and A549 cell migration and invasion, but the agonist carbachol promoted the migration and invasion of these three cell lines | 30027929 |
| 2018-01-20 10:15:00 | The study was focused on the human mAChR1 receptor for which a presumably reliable model was generated using the congener mAChR3 as the template along with a second less reliable model based on the distant beta2-AR template. The second model was then utilized to produce the chimeras by combining the conformations of its Pro-containing helices (i.e., TM4, TM5, TM6 and TM7 with 16 modeled chimeras). | 27490167 |
| 2017-06-10 10:58:00 | he discovery of a receptor homolog of human mAChR1 on Acanthamoeba with future studies planned to show its expression and binding to cholinergic agonist and antagonist would help clarify its role in the biology of this protist pathogen. | 27601178 |
| Type | IDs |
|---|---|
| Synonymous | HM1, M1, M1R |
| Gene |
UniProtKB-ID:
ACM1_HUMAN,
Q53XZ3_HUMAN
UniprotKB:
P11229,
Q53XZ3
UniParc:
UPI00001252AB,
UPI0000070C23
EMBL:
BC022984,
X15263,
AP000438,
AK312374,
BT007166,
BC007740,
AF498915,
AF385587,
X52068,
Y00508,
CH471076
Ensembl:
ENSG00000168539
KO:
hsa:1128
|
| Nucleutide sequences |
EMBL-CDS:
AAK68112.1,
CAA36291.1,
CAA33334.1,
AAH22984.1,
AAM18938.1,
CAA68560.1,
AAH07740.1,
EAW74126.1,
BAG35292.1,
EAW74125.1,
EAW74124.1,
AAP35830.1
Gene_ORFName:
hCG_2020133
Ensembl_TRS:
ENST00000543973,
ENST00000306960
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441188,
ENSP00000306490
RefSeq:
XP_011543044.1,
NP_000729.2
|
| Others |
UniRef100:
UniRef100_P11229
UniRef90:
UniRef90_P11229
UniRef50:
UniRef50_P11229
UniGene:
Hs.632119
CCDS:
CCDS8040.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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