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11277 TREX1

11277

TREX1

three prime repair exonuclease 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition three prime repair exonuclease 1

研究结论

Date Results Publications
2021-04-03 13:36:00 TREX1 - Apex predator of cytosolic DNA metabolism. 32615442
2021-03-06 13:31:00 ER-directed TREX1 limits cGAS activation at micronuclei. 33476576
2021-03-06 13:31:00 cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing. 33606975
2021-03-06 13:25:00 Familial chilblain lupus due to a novel mutation in TREX1 associated with Aicardi-Goutie'res syndrome. 32293470
2020-10-31 13:17:00 APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis. 32719516

名称对应

Type IDs
Synonymous AGS1, CRV, DRN3, HERNS
Gene
UniProtKB-ID: TREX1_HUMAN, Q5TZT0_HUMAN
UniprotKB: Q9NSU2, Q5TZT0
UniParc: UPI000007301C, UPI00000411D8, UPI000006EBDE
EMBL: AF319566, AF319569, AK315196, BT020053, AL137745, AF151105, BT020052, AF483777, AF319567, CH471055, AJ243797, BC023630, AF319568
Ensembl: ENSG00000213689
KO: hsa:11277
Nucleutide sequences
EMBL-CDS: AAK07616.1, AAK07613.1, CAB50866.1, AAH23630.1, BAG37636.1, AAK07614.1, AAL82504.1, AAD48774.2, AAK07615.1, EAW64883.1, AAV38856.1, AAV38855.1
Gene_ORFName: hCG_1997849
Ensembl_TRS: ENST00000625293, ENST00000444177
Protein sequencees
Ensembl_PRO: ENSP00000415972, ENSP00000486676
RefSeq: NP_338599.1, NP_009179.2
Others
UniRef100: UniRef100_Q9NSU2
UniRef90: UniRef90_Q9NSU2
UniRef50: UniRef50_Q91XB0
UniGene: Hs.707026, Hs.713742, Hs.744646
CCDS: CCDS59451.1, CCDS2769.1

全选

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