| Type | Description |
|---|---|
| Definition | SP140 nuclear body protein |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 11:14:00 | The Sp140 is multi-SUMOylated and its PHD finger works as versatile protein-protein interaction platform promoting intramolecular SUMOylation of the adjacent BRD. | 30465816 |
| 2019-05-18 11:50:00 | Our findings showed that SP140 is an important repressor of genes implicated in inflammation, suggesting that decreased expression of SP140, promoted by the rs28445040-T risk variant, may lead to up-regulation of these genes by means of NF-kappaB inhibition in B cells. | 30102396 |
| 2016-12-17 11:25:00 | IL1R2 hypomethylation and androgen receptor hypermethylation may constitute an important determinant of disease severity, whereas NPR2 hypomethylation and SP140 hypermethylation may provide a biomarker for vulnerability to excessive daytime sleepiness in Obstructive Sleep Apnea | 26888452 |
| 2016-07-16 11:36:00 | Data identified rs28445040 variant in SP140 gene as the causal factor for skipping of exon 7 and the most associated with multiple sclerosis. | 26152201 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20731705 |
| Type | IDs |
|---|---|
| Synonymous | LYSP100, LYSP100-A, LYSP100-B |
| Gene |
UniProtKB-ID:
SP140_HUMAN,
B4DVW8_HUMAN,
Q8IWJ1_HUMAN,
Q0VGE4_HUMAN
UniprotKB:
Q13342,
B4DVW8,
Q8IWJ1,
Q0VGE4
UniParc:
UPI0000E07F02,
UPI00000744D4,
UPI000035ECB1,
UPI00015E0ACB,
UPI0000DBE1A1,
UPI000185D560,
UPI0000EE3852,
UPI0000209746,
UPI00017A7DFC
EMBL:
BC070160,
BC038091,
CH471063,
BC105744,
BC105743,
AK301267,
BC105960,
U63420,
U36500,
AC009950,
AC009949,
U36499
Ensembl:
ENSG00000079263
KO:
hsa:11262
|
| Nucleutide sequences |
EMBL-CDS:
AAI05961.1,
AAX93282.1,
EAW70922.1,
AAH70160.1,
AAC50817.1,
AAI05744.1,
AAB18617.1,
AAX88868.1,
AAB18616.1,
BAG62830.1,
AAH38091.1,
AAI05745.1
Ensembl_TRS:
ENST00000420434,
ENST00000392045,
ENST00000373645,
ENST00000343805,
ENST00000417495
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398210,
ENSP00000393618,
ENSP00000375899,
ENSP00000342096,
ENSP00000362749
RefSeq:
XP_005246313.1,
XP_016858733.1,
NP_001265381.1,
XP_016858741.1,
XP_005246310.1,
NP_001265382.1,
XP_016858729.1,
XP_016858739.1,
XP_016858738.1,
XP_011508818.1,
XP_005246312.1,
XP_011508819.1,
XP_011508822.1,
NP_009168.4,
XP_005246309.1,
XP_016858730.1,
XP_011508820.1,
NP_001005176.1,
XP_011508821.1,
XP_016858740.1,
XP_016858728.1,
NP_001265380.1,
XP_016858734.1,
XP_016858736.1,
XP_016858735.1,
XP_005246311.1,
XP_011508817.1,
XP_016858731.1,
XP_016858737.1,
XP_016858742.1,
XP_016858732.1,
XP_006712286.1
|
| Others |
UniRef100:
UniRef100_Q8IWJ1,
UniRef100_Q13342,
UniRef100_Q0VGE4,
UniRef100_B4DVW8
UniRef90:
UniRef90_Q8IWJ1,
UniRef90_Q13342
UniRef50:
UniRef50_Q13342,
UniRef50_Q8IWJ1
UniGene:
Hs.632549
CCDS:
CCDS33392.1,
CCDS63150.1,
CCDS63151.1,
CCDS42831.1,
CCDS63149.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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