| Type | Description |
|---|---|
| Definition | melanocortin 2 receptor accessory protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | Membrane orientation and oligomerization of the melanocortin receptor accessory protein 2. | 32943551 |
| 2020-12-12 13:21:00 | The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a. | 31911434 |
| 2020-01-25 13:16:00 | The pleiotropic metabolic effect of loss-of-function mutations in MRAP2 might be due to the failure of different MRAP2-regulated G-protein-coupled receptors in various tissues including pancreatic islets. | 31700171 |
| 2019-05-18 11:23:00 | Data found that MRAP2 was significantly up-regulated in women with unexplained infertility. The epithelium of the uterine glands showed hypertrophy in women with unexplained infertility. MRAP2 expression alteration in the endometrium on infertile women suggestes a potential role in regulating endometrial stability. | 30951854 |
| 2018-12-01 11:29:00 | The accepted idea that melanocortin Receptor Accessory Proteins (MRAPs) are specific regulators of melanocortin receptors was recently challenged by the discovery that MRAP2 inhibits the activity of prokineticin receptors. Recent studies are starting to explain the role of the unusual structure of MRAPs and to illustrate the importance of MRAP2 for the maintenance of both energy and glucose homeostasis. [review] | 28499989 |
| Type | IDs |
|---|---|
| Synonymous | C6orf117, bA51G5.2 |
| Gene |
UniProtKB-ID:
MRAP2_HUMAN
UniprotKB:
Q96G30
UniParc:
UPI0000074376
EMBL:
AK292736,
AL161621,
CH471051,
BC039855,
AK090775,
BC010003
Ensembl:
ENSG00000135324
KO:
hsa:112609
|
| Nucleutide sequences |
EMBL-CDS:
EAW48646.1,
BAC03517.1,
AAH39855.1,
AAH10003.2,
BAF85425.1
Ensembl_TRS:
ENST00000257776
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257776
RefSeq:
XP_016865709.1,
NP_001333471.1,
NP_001333472.1,
XP_016865710.1,
NP_612418.2,
XP_024302086.1,
NP_001333473.1,
NP_001333470.1
|
| Others |
UniRef100:
UniRef100_Q96G30
UniRef90:
UniRef90_Q96G30
UniRef50:
UniRef50_Q96G30
UniGene:
Hs.370055
CCDS:
CCDS5001.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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