| Type | Description |
|---|---|
| Definition | filamin A interacting protein 1 like |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 10:37:00 | FILIP1L inhibits progression in colorectal cancer by inhibiting tumor cell proliferation and angiogenesis. | 27750216 |
| 2018-02-17 11:17:00 | Studies have shown that FILIP1L expression is related with inhibition of metastases and chemoresistance of ovarian neoplasm, which is associated with downregulation of EMT through beta-catenin degradation. FILIP1L expression correlates with significantly improved overall survival. | 27776341 |
| 2016-10-17 14:08:00 | these findings suggest that FILIP1L reduces beta-catenin levels, which may lead to the transcriptional downregulation of WNT target genes such as MMPs, resulting in inhibition of metastasis | 24327474 |
| 2014-09-20 10:59:00 | down-regulation of FILIP1L associated with DNA methylation is related with the invasive phenotype in various cancers. | 24340050 |
| 2013-08-31 12:36:00 | In addition, eight genes classified as 'second tier' hits in the original study (PAX7, THADA, COL8A1/FILIP1L, DCAF4L2, GADD45G, NTN1, RBFOX3 and FOXE1) showed evidence of linkage and association in this replication sample. | 23512105 |
| Type | IDs |
|---|---|
| Synonymous | DOC-1, DOC1, GIP130, GIP90 |
| Gene |
UniProtKB-ID:
FIL1L_HUMAN
UniprotKB:
Q4L180
UniParc:
UPI00001B24B2,
UPI000192C275,
UPI000192C274,
UPI00015F45E1,
UPI000006D3CD,
UPI00005EDD8B,
UPI00001B24B4
EMBL:
AF514869,
AC117419,
AY642382,
CH471052,
EU531865,
AC069222,
BC020941,
AC024938,
AF514868,
EU531866,
U53445,
BC027860,
AF329092,
AF514867
Ensembl:
ENSG00000168386
KO:
hsa:11259
|
| Nucleutide sequences |
EMBL-CDS:
AAQ08177.1,
AAH27860.1,
AAQ08178.1,
ACB37437.1,
AAV34207.1,
AAA98972.1,
AAN16206.1,
AAQ08179.1,
ACB37436.1,
EAW79833.1,
AAH20941.1
Ensembl_TRS:
ENST00000487087,
ENST00000471562,
ENST00000331335,
ENST00000383694,
ENST00000398326,
ENST00000354552
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346560,
ENSP00000381371,
ENSP00000327880,
ENSP00000373192,
ENSP00000419642,
ENSP00000417774
RefSeq:
NP_001035924.1,
NP_055705.2,
XP_011510673.1,
NP_001374781.1,
NP_001357176.1,
NP_001269723.1,
NP_001374779.1,
NP_001269722.1,
NP_001374780.1,
NP_878913.2
|
| Others |
UniRef100:
UniRef100_Q4L180
UniRef90:
UniRef90_Q4L180
UniRef50:
UniRef50_Q4L180
UniGene:
Hs.104672
CCDS:
CCDS63700.1,
CCDS74969.1,
CCDS43117.1,
CCDS43118.1,
CCDS43119.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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