| Type | Description |
|---|---|
| Definition | TP53 target 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:26:00 | Survival analysis for long noncoding RNAs identifies TP53TG1 as an antioncogenic target for the breast cancer. | 32020607 |
| 2019-10-05 12:03:00 | TP53TG1 could directly bind to miR-96 and effectively function as a sponge for miR-96, antagonizing the functions of miR-96 and leading to derepression of KRAS, which is a core oncogene in the initiation and maintenance of pancreatic ductal adenocarcinoma (PDAC). TP53TG1 contributes to the growth and progression of PDAC by acting as a competing endogenous RNA to competitively bind to miR-96 and regulate KRAS expression. | 31325400 |
| 2018-04-21 10:54:00 | Study reports that TP53TG1 is an lncRNA that is critical for the correct response of p53 to DNA damage. The cancer growth suppressor features of TP53TG1 are linked to its ability to block the tumorigenic activity of the RNA binding protein YBX1. The DNA methylation-associated silencing of TP53TG1 produces aggressive tumors that are resistant to cellular death when DNAdamaging agents and small targeted molecules are used. | 27821766 |
| 2018-01-06 11:25:00 | data showed that TP53TG1 under glucose deprivation may promote cell proliferation and migration by influencing the expression of glucose metabolism related genes in glioma. | 28569381 |
| 2015-11-07 11:38:00 | From our analysis, variants in the genes ABCB4, TP53AIP1, ARHGAP32 and TMEM88B were identified linked to the alexithymia phenotype. | 25882097 |
| Type | IDs |
|---|---|
| Synonymous | LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees | |
| Others |
UniGene:
Hs.274329
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32020607 |
J Cell Physiol Mei Shao , Huali Ma , Xing Wan , Yuhai Liu |
2020-10-01 | - |
| 31325400 |
Cancer Sci Yufeng Zhang , Haiyan Yang , Yong Du , Pingping Liu , Jing Zhang , Yue Li , Haitao Shen , Lingxiao Xing , Xiaoying Xue , Jie Chen , Xianghong Zhang |
2019-09-01 | - |
| 29588850 |
Cell Biosci Huijuan Xiao , Yihe Liu , Pan Liang , Bo Wang , Hongna Tan , Yonggao Zhang , Xianzheng Gao , Jianbo Gao |
2018-01-01 | - |
| 28569381 |
LncRNA-TP53TG1 Participated in the Stress Response Under Glucose Deprivation in Glioma. J. Cell. Biochem. Xin Chen , Yang Gao , Deheng Li , Yiqun Cao , Bin Hao |
2017-12-01 | - |
| 27821766 |
Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. Proc. Natl. Acad. Sci. U.S.A. Angel Diaz-Lagares , Ana B Crujeiras , Paula Lopez-Serra , Marta Soler , Fernando Setien , Ashish Goyal , Juan Sandoval , Yutaka Hashimoto , Anna Martinez-Cardús , Antonio Gomez , Holger Heyn , Catia Moutinho , Jesús Espada , August Vidal , Maria Paúles , Maica Galán , Núria Sala , Yoshimitsu Akiyama , MarÃa MartÃnez-Iniesta , Lourdes Farré , Alberto Villanueva , Matthias Gross , Sven Diederichs , Sonia Guil , Manel Esteller |
2016-11-22 | - |
| 25882097 |
Analysis of functional variants reveals new candidate genes associated with alexithymia. Psychiatry Res Massimo Mezzavilla , Sheila Ulivi , Martina La Bianca , Davide Carlino , Paolo Gasparini , Antonietta Robino |
2015-06-30 |
TP53TG1,
TMEM8B,
ABCB4
|
| 21832049 |
J Biol Chem Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária Szũcs , Ferenc Orosz , Botond Penke , Judit Ovádi |
2011-09-30 | - |
| 12690205 |
Human chromosome 7: DNA sequence and biology. Science Stephen W Scherer , Joseph Cheung , Jeffrey R MacDonald , Lucy R Osborne , Kazuhiko Nakabayashi , Jo-Anne Herbrick , Andrew R Carson , Layla Parker-Katiraee , Jennifer Skaug , Razi Khaja , Junjun Zhang , Alexander K Hudek , Martin Li , May Haddad , Gavin E Duggan , Bridget A Fernandez , Emiko Kanematsu , Simone Gentles , Constantine C Christopoulos , Sanaa Choufani , Dorota Kwasnicka , Xiangqun H Zheng , Zhongwu Lai , Deborah Nusskern , Qing Zhang , Zhiping Gu , Fu Lu , Susan Zeesman , Malgorzata J Nowaczyk , Ikuko Teshima , David Chitayat , Cheryl Shuman , Rosanna Weksberg , Elaine H Zackai , Theresa A Grebe , Sarah R Cox , Susan J Kirkpatrick , Nazneen Rahman , Jan M Friedman , Henry H Q Heng , Pier Giuseppe Pelicci , Francesco Lo-Coco , Elena Belloni , Lisa G Shaffer , Barbara Pober , Cynthia C Morton , James F Gusella , Gail A P Bruns , Bruce R Korf , Bradley J Quade , Azra H Ligon , Heather Ferguson , Anne W Higgins , Natalia T Leach , Steven R Herrick , Emmanuelle Lemyre , Chantal G Farra , Hyung-Goo Kim , Anne M Summers , Karen W Gripp , Wendy Roberts , Peter Szatmari , Elizabeth J T Winsor , Karl-Heinz Grzeschik , Ahmed Teebi , Berge A Minassian , Juha Kere , Lluis Armengol , Miguel Angel Pujana , Xavier Estivill , Michael D Wilson , Ben F Koop , Sabrina Tosi , Gudrun E Moore , Andrew P Boright , Eitan Zlotorynski , Batsheva Kerem , Peter M Kroisel , Erwin Petek , David G Oscier , Sarah J Mould , Hartmut Döhner , Konstanze Döhner , Johanna M Rommens , John B Vincent , J Craig Venter , Peter W Li , Richard J Mural , Mark D Adams , Lap-Chee Tsui |
2003-05-02 |
BET1P1,
LOC100129603,
TUBB3P2,
C7orf72,
LOC100131859,
LOC100286906,
HSPA8P8,
LOC100287825,
DNAJB6,
LINC01006,
LOC100506557,
TMEM178B,
ABCF2,
ARPC1B,
ARL4A,
NAMPT,
AKAP9,
AASS,
LOC101927181,
CDK5,
CDK6,
POP7,
RAMP3,
LOC102724434,
BET1,
IKZF1,
SEMA3A,
NOD1,
GPNMB,
SEMA3C,
AGR2,
ARPC1A,
IGF2BP3,
YKT6,
ADCY1,
CFTR,
FGL2,
CPSF4,
FASTK,
COPS6,
KDELR2,
DUS4L,
NUPL2,
HIBADH,
ZNF277,
CHN2,
TP53TG1,
CHRM2,
GLCCI1,
FKBP9,
CBX3,
ZBED6CL,
TSGA13,
GPR146,
MALSU1,
AGAP3,
ADCYAP1R1,
CLK2P1,
C7orf13,
OR9A4,
CPA1,
C7orf34,
TMEM139,
OR2F2,
SSU72P8,
PRSS37,
KLF14,
SSMEM1,
MTPN,
LRGUK,
ASB10,
PRSS58,
MPLKIP,
ASZ1,
CRHR2,
RUNDC3B,
LINC00689,
KCTD7,
C7orf66,
GIMAP8,
CRYGN,
ZNF425,
CYP3A7,
AMZ1,
RBM33,
AGR3,
CYP3A4,
CYP3A5,
CYP51A1,
DGKB,
DDC,
AEBP1,
GALNTL5,
RNF133,
THAP5,
CCDC71L,
GIMAP7,
BHLHA15,
BMPER
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 9713990 |
Genes Chromosomes Cancer Y Takei , S Ishikawa , T Tokino , T Muto , Y Nakamura |
1998-09-01 |
TP53TG1
|
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