| Type | Description |
|---|---|
| Definition | histamine receptor H3 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:51:00 | These findings revealed that HRH3 serves an important role in the growth and metastasis of hepatocellular carcinomacells, which provides experimental evidence supporting the application of HRH3 as a potential therapeutic target in hepatocellular carcinoma treatment | 31002350 |
| 2018-09-22 11:02:00 | These results indicate that in SH-SY5Y cells, hH3R445 and hH3R365 isoforms regulate in a differential manner the signaling pathways triggered by receptor activation. | 29557708 |
| 2018-02-03 11:11:00 | results indicate that the single-point Y197C mutation, in the aminus region of TM5 of the hH3R445, does not affect the expression, ligand binding or signaling of the receptor | 28126588 |
| 2018-01-13 12:44:00 | We detected high H3R expression in oligodendroglial cells from demyelination lesions in human samples of patients with MS, and validated a genetic association between an exonic single nucleotide polymorphism in HRH3 and susceptibility to multiple sclerosis. | 29253893 |
| 2016-12-17 11:28:00 | These findings for the first time screen out one SNP (rs3787429) of HRH3 gene that was significantly associated with CHF in Chinese Han population | 26989676 |
| Type | IDs |
|---|---|
| Synonymous | GPCR97, HH3R |
| Gene |
UniProtKB-ID:
HRH3_HUMAN
UniprotKB:
Q9Y5N1
UniParc:
UPI000012C6ED,
UPI000002AB10,
UPI000002AB0E,
UPI000002AB0D,
UPI000002AB12,
UPI000002AB0F,
UPI000002AB11
EMBL:
BC096840,
AF363791,
AB045369,
AJ278250,
AL078633,
AF140538,
AJ296652,
AB019000
Ensembl:
ENSG00000101180
KO:
hsa:11255
|
| Nucleutide sequences |
EMBL-CDS:
CAC39434.1,
AAD38151.1,
BAB20090.1,
AAK50040.1,
CAC51025.1,
AAH96840.1,
BAB17030.1
Ensembl_TRS:
ENST00000340177
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342560
RefSeq:
XP_016883112.1,
NP_009163.2,
XP_005260323.1
|
| Others |
UniRef100:
UniRef100_Q9Y5N1
UniRef90:
UniRef90_Q9Y5N1
UniRef50:
UniRef50_Q9Y5N1
UniGene:
Hs.251399
CCDS:
CCDS13493.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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