| Type | Description |
|---|---|
| Definition | egl-9 family hypoxia-inducible factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 12:08:00 | PHD3 and PHD2 depletion leads to dilated cardiomyopathy and exacerbates cardiac injury. | 31356139 |
| 2020-01-11 12:18:00 | obstructive sleep apnea-induced cardiovascular fibrosis was associated with smooth muscle cells dedifferentiation, and PHD3 overexpression may benefit its prevention by reversing the dedifferentiation. Therefore, PHD3 overexpression has therapeutic potential in disease treatment. | 31346526 |
| 2019-11-02 10:52:00 | glucagon-inducible PHD3 regulates glucose metabolism by suppressing stress signalling and optimising gluconeogenesis and insulin signalling in hepatocytes. | 30250231 |
| 2018-11-03 11:00:00 | we identified the beta2 adrenergic receptor (ADRB2) as a downstream target for PHD3 in skeletal muscle | 28939592 |
| 2018-07-07 10:48:00 | PHD2 and PHD3 are essential for normal kidney development as the combined inactivation of stromal PHD2 and PHD3 resulted in renal failure that was associated with reduced kidney size, decreased numbers of glomeruli, and abnormal postnatal nephron formation. | 28847650 |
| Type | IDs |
|---|---|
| Synonymous | 2610021G09Rik, AI505553, AI648162, Hif-p4h-3, Phd3, SM-20 |
| Gene |
UniProtKB-ID:
EGLN3_MOUSE,
A0A0R4J0H9_MOUSE
UniprotKB:
Q91UZ4,
A0A0R4J0H9
UniParc:
UPI00000290C1,
UPI0000024AF0
EMBL:
AK165972,
BC069893,
AK044787,
AJ310548,
AK170732,
BC022961,
AC115785,
BC058278,
AF421882,
BC044926
Ensembl:
ENSMUSG00000035105
KO:
mmu:112407
|
| Nucleutide sequences |
EMBL-CDS:
BAC32092.1,
AAH69893.1,
BAE38492.1,
AAH58278.1,
AAL17824.1,
AAH44926.1,
BAE41988.1,
AAH22961.1,
CAC42517.1
Ensembl_TRS:
ENSMUST00000039516
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041874
RefSeq:
XP_036013061.1,
NP_082409.2
|
| Others |
UniRef100:
UniRef100_A0A0R4J0H9,
UniRef100_Q91UZ4
UniRef90:
UniRef90_Q9H6Z9,
UniRef90_Q91UZ4
UniRef50:
UniRef50_Q9H6Z9,
UniRef50_Q91UZ4
UniGene:
Mm.133037
CCDS:
CCDS25908.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员