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112399 EGLN3

112399

EGLN3

egl-9 family hypoxia inducible factor 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition egl-9 family hypoxia inducible factor 3

研究结论

Date Results Publications
2020-07-18 11:37:00 Interaction among oncogenic miR-31, EGLN3 down-regulation, and inflammation was documented in human esophageal squamous cell carcinoma tissues. 32123074
2020-06-13 11:04:00 This is the first crystal report of PHD3/PKM2 complex as well as this study demonstrates a direct physical binding through protein-protein interaction. 31760602
2020-05-02 10:19:00 EGLN3 polymorphism is associated with High-Altitude Polycythemia. 31827636
2020-02-22 10:58:00 The authors did not detect prolyl-hydroxylase activity on any reported non-HIF protein or peptide, using conditions supporting robust HIF-alpha hydroxylation. 31500697
2019-12-14 12:13:00 PHD3 regulates p53 stability through hydroxylation of p53 at proline 359. 30067985

名称对应

Type IDs
Synonymous HIFP4H3, HIFPH3, PHD3
Gene
UniProtKB-ID: EGLN3_HUMAN, Q3T1B0_HUMAN, F8W1G2_HUMAN, B3KVT0_HUMAN
UniprotKB: Q9H6Z9, Q3T1B0, F8W1G2, B3KVT0
UniParc: UPI0000052C42, UPI0000D475FF, UPI00001FD3BD, UPI000004F8A8
EMBL: BC064924, BC111057, AJ310545, BC010992, AK025273, AK123350, AL162191, BC105938, BC102030, AL358340, BC105939, KF455858, KF455855, AL358274, KC877527, KF455864
Ensembl: ENSG00000129521
KO: hsa:112399
Nucleutide sequences
EMBL-CDS: AAH64924.2, CAC42511.1, AAI05940.1, BAB15101.1, AAH10992.3, AAI11058.2, AAI05939.1, AAI02031.1, BAG53892.1
Ensembl_TRS: ENST00000250457, ENST00000553215
Protein sequencees
Ensembl_PRO: ENSP00000250457, ENSP00000447470
RefSeq: NP_071356.1, NP_001295032.1
Others
UniRef100: UniRef100_Q9H6Z9, UniRef100_F8W1G2, UniRef100_B3KVT0
UniRef90: UniRef90_F8W1G2, UniRef90_Q9H6Z9
UniRef50: UniRef50_Q9H6Z9, UniRef50_A0A452U0L8
UniGene: Hs.135507
CCDS: CCDS9646.1

全选

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