| Type | Description |
|---|---|
| Definition | egl-9 family hypoxia inducible factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:54:00 | Association of EGLN2 rs10680577 Polymorphism with the Risk and Clinicopathological Features of Patients with Prostate Cancer. | 32458625 |
| 2020-06-13 12:36:00 | Meta-analysis showed that EGLN2 rs10680577 polymorphism was significantly associated with cancer risk. | 31414584 |
| 2020-05-16 12:58:00 | Study consistently found that hypermethylation at cg25923056-EGLN2 downregulated the corresponding gene EGLN2 expression in lung adenocarcinomas (LUAD) tumor tissues. Meanwhile, EGLN2 expression was negatively correlated with HIF1A expression in tumor tissues and significantly interacted with HIF1A expression on overall survival. | 30665327 |
| 2020-03-14 10:50:00 | Adenylosuccinate lyase (ADSL) is an EglN2 hydroxylase substrate in triple negative breast cancer. | 31729379 |
| 2020-02-22 10:58:00 | The authors did not detect prolyl-hydroxylase activity on any reported non-HIF protein or peptide, using conditions supporting robust HIF-alpha hydroxylation. | 31500697 |
| Type | IDs |
|---|---|
| Synonymous | EIT-6, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1 |
| Gene |
UniProtKB-ID:
EGLN2_HUMAN,
A0A024R0R2_HUMAN
UniprotKB:
Q96KS0,
A0A024R0R2
UniParc:
UPI0000050C8F,
UPI0001C67A9E
EMBL:
AJ310544,
BC001723,
AK291385,
AL832506,
AY040565,
AC008537,
BC036051,
CH471126
Ensembl:
ENSG00000269858
KO:
hsa:112398
|
| Nucleutide sequences |
EMBL-CDS:
CAC42510.1,
BAF84074.1,
AAK82943.1,
EAW57008.1,
AAH36051.1,
AAH01723.1,
EAW57009.1,
EAW57010.1,
EAW57011.1
Gene_ORFName:
hCG_20789
Ensembl_TRS:
ENST00000406058,
ENST00000303961,
ENST00000593726
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000469686,
ENSP00000307080,
ENSP00000385253
RefSeq:
NP_444274.1,
NP_542770.2
|
| Others |
UniRef100:
UniRef100_Q96KS0
UniRef90:
UniRef90_Q96KS0
UniRef50:
UniRef50_Q96KS0
UniGene:
Hs.515417,
Hs.730737
CCDS:
CCDS12567.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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