Type | Description |
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Definition | systemic lupus erythmatosus susceptibility 2 |
Date | Results | Publications |
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2013-01-26 10:51:00 | These results show that Sle2c1 contributes to lupus pathogenesis by affecting T cell differentiation in combination with other susceptibility loci, such as lpr. | 21360506 |
2012-09-08 11:05:00 | Mice of the B6.NZMSle1/Sle2/Sle3 (Sle1,2,3) lupus-prone strain also express an interferon (IFN) signature compared with non-autoimmune C57BL/6 mice. | 22661089 |
2012-08-11 11:27:00 | The -74C-to-T single nucleotide polymorphism (SNP) plays a functional role in decreasing p18/Inc4c expression in association with the Sle2c1 lupus susceptibility locus. | 22504641 |
2011-10-08 10:42:00 | study showed that at least two Sle2 genes are involved in the activation of anti-DNA B cells. | 21270826 |
2011-06-18 10:35:00 | The Sle2c2 locus of New Zealand Black mice contains a potent lupus susceptibility gene which suppresses T cell-induced autoimmune responses through myeloid-derived suppressor cells. | 21335485 |
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