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112365 Sle3

112365

Sle3

systemic lupus erythmatosus susceptibility 3

unknown

Mus musculus

基因描述

Type Description
Definition systemic lupus erythmatosus susceptibility 3

研究结论

Date Results Publications
2012-09-08 11:05:00 Mice of the B6.NZMSle1/Sle2/Sle3 (Sle1,2,3) lupus-prone strain also express an interferon (IFN) signature compared with non-autoimmune C57BL/6 mice. 22661089
2010-01-21 00:00:00 The immunomodulatory effects of prolactin are genetically determined in C57BL/6 mice by genes which lie within the lupus susceptibility interval Sle3/5. 16849443
2010-01-21 00:00:00 On the nonautoimmune C57BL/6 background, Sle3 affects Ig VHDJH junctional diversity and Ig variable region heavy chain mutational diversity and leads to recombinational activation of allelically excluded Ig heavy chain genes in the periphery. 15585861
2010-01-21 00:00:00 The pathways mediated by Sle3/5 critical lupus susceptibility loci derived from the New Zealand White strain must be integrated intracellularly for epistatic interactions to occur 16002739

名称对应

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