| Type | Description |
|---|---|
| Definition | ring finger protein 139 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:08:00 | INSIG1 coordinated with another ligase, translocation in renal carcinoma chromosome 8 (TRC8), and promoted Gag degradation through the lysosome pathway. | 30563842 |
| 2019-04-20 10:58:00 | TRC8 and MARCH6 depletion altered the turnover of the tail-anchored protein heme oxygenase-1. | 29519897 |
| 2018-03-31 12:18:00 | Low RNF139 expression is associated with progression of tongue cancer. | 28662643 |
| 2017-07-08 12:27:00 | interaction with Bag1 then shifts hERG degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating enzyme Ube2g2, as determined by siRNA screening | 27998983 |
| 2016-01-30 10:16:00 | TRC8 and TMEM129 are endoplasmic reticulum-associated degradation ubiquitin E3 ligases for viral and cellular targeting of MHC class I. (Review) | 26210183 |
| Type | IDs |
|---|---|
| Synonymous | HRCA1, RCA1, TRC8 |
| Gene |
UniProtKB-ID:
RN139_HUMAN
UniprotKB:
Q8WU17
UniParc:
UPI0000071331
EMBL:
BC064636,
CH471060,
AF064801,
AF064800,
BC021571,
AK001602
Ensembl:
ENSG00000170881
KO:
hsa:11236
|
| Nucleutide sequences |
EMBL-CDS:
AAC39931.1,
BAG50947.1,
EAW92064.1,
AAH64636.1,
AAC39930.1,
AAH21571.1
Ensembl_TRS:
ENST00000303545
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304051
RefSeq:
NP_009149.2
|
| Others |
UniRef100:
UniRef100_Q8WU17
UniRef90:
UniRef90_Q8WU17
UniRef50:
UniRef50_Q8WU17
UniGene:
Hs.744151
CCDS:
CCDS6350.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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