Type | Description |
---|---|
Definition | programmed cell death 10 |
Date | Results | Publications |
---|---|---|
2020-10-24 14:08:00 | Emerging roles of CCM genes during tumorigenesis with potential application as novel biomarkers across major types of cancers. | 32186778 |
2020-09-12 16:02:00 | Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. | 31776290 |
2019-11-02 11:05:00 | showed a population-specific mutational and clinical spectrum of multiple CCMs. These findings broaden the mutational spectrum in CCMs and highlight the importance of screening for deletions in the CCM genes in patients with multiple CCMs | 29749609 |
2019-10-12 10:04:00 | Study identified a novel large deletion in PDCD10 gene in patients with cerebral cavernous malformation (CCM) and explored its cellular effect which associated with significant reduction of interactions between KRIT1 and CCM2, and impaired autophagy process. | 30161288 |
2019-04-20 10:55:00 | Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma, suggesting PDCD10 as a potential target for glioblastoma therapy. | 30392087 |
Type | IDs |
---|---|
Synonymous | CCM3, TFAR15 |
Gene |
UniProtKB-ID:
PDC10_HUMAN,
C9J363_HUMAN
UniprotKB:
Q9BUL8,
C9J363
UniParc:
UPI0000071E33,
UPI0000E5AA89
EMBL:
AF022385,
BC016353,
AC079822,
AK291130,
CR457107,
BC002506,
CH471052
Ensembl:
ENSG00000114209
KO:
hsa:11235
|
Nucleutide sequences |
EMBL-CDS:
CAG33388.1,
EAW78580.1,
EAW78581.1,
EAW78574.1,
EAW78578.1,
AAH16353.1,
EAW78577.1,
EAW78575.1,
AAB72225.1,
BAF83819.1,
EAW78576.1,
AAH02506.1,
EAW78579.1
Gene_ORFName:
hCG_27561
Ensembl_TRS:
ENST00000392750,
ENST00000470131,
ENST00000473645,
ENST00000497056,
ENST00000461494,
ENST00000492396
|
Protein sequencees |
Ensembl_PRO:
ENSP00000376506,
ENSP00000420021,
ENSP00000420553,
ENSP00000418317,
ENSP00000417202,
ENSP00000417309
RefSeq:
XP_024309098.1,
XP_006713548.1,
XP_024309099.1,
XP_011510671.1,
XP_016861134.1,
XP_005247145.1,
XP_024309097.1,
XP_005247143.1,
XP_016861133.1,
XP_005247144.1,
XP_011510670.1,
NP_009148.2,
NP_665858.1,
NP_665859.1
|
Others |
UniRef100:
UniRef100_Q9BUL8
UniRef90:
UniRef90_Q9BUL8
UniRef50:
UniRef50_Q9BUL8
UniGene:
Hs.478150
CCDS:
CCDS3202.1
|
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Refseq |
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