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11235 PDCD10

11235

PDCD10

programmed cell death 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition programmed cell death 10

研究结论

Date Results Publications
2020-10-24 14:08:00 Emerging roles of CCM genes during tumorigenesis with potential application as novel biomarkers across major types of cancers. 32186778
2020-09-12 16:02:00 Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. 31776290
2019-11-02 11:05:00 showed a population-specific mutational and clinical spectrum of multiple CCMs. These findings broaden the mutational spectrum in CCMs and highlight the importance of screening for deletions in the CCM genes in patients with multiple CCMs 29749609
2019-10-12 10:04:00 Study identified a novel large deletion in PDCD10 gene in patients with cerebral cavernous malformation (CCM) and explored its cellular effect which associated with significant reduction of interactions between KRIT1 and CCM2, and impaired autophagy process. 30161288
2019-04-20 10:55:00 Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma, suggesting PDCD10 as a potential target for glioblastoma therapy. 30392087

名称对应

Type IDs
Synonymous CCM3, TFAR15
Gene
UniProtKB-ID: PDC10_HUMAN, C9J363_HUMAN
UniprotKB: Q9BUL8, C9J363
UniParc: UPI0000071E33, UPI0000E5AA89
EMBL: AF022385, BC016353, AC079822, AK291130, CR457107, BC002506, CH471052
Ensembl: ENSG00000114209
KO: hsa:11235
Nucleutide sequences
EMBL-CDS: CAG33388.1, EAW78580.1, EAW78581.1, EAW78574.1, EAW78578.1, AAH16353.1, EAW78577.1, EAW78575.1, AAB72225.1, BAF83819.1, EAW78576.1, AAH02506.1, EAW78579.1
Gene_ORFName: hCG_27561
Ensembl_TRS: ENST00000392750, ENST00000470131, ENST00000473645, ENST00000497056, ENST00000461494, ENST00000492396
Protein sequencees
Ensembl_PRO: ENSP00000376506, ENSP00000420021, ENSP00000420553, ENSP00000418317, ENSP00000417202, ENSP00000417309
RefSeq: XP_024309098.1, XP_006713548.1, XP_024309099.1, XP_011510671.1, XP_016861134.1, XP_005247145.1, XP_024309097.1, XP_005247143.1, XP_016861133.1, XP_005247144.1, XP_011510670.1, NP_009148.2, NP_665858.1, NP_665859.1
Others
UniRef100: UniRef100_Q9BUL8
UniRef90: UniRef90_Q9BUL8
UniRef50: UniRef50_Q9BUL8
UniGene: Hs.478150
CCDS: CCDS3202.1

全选

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