| Type | Description |
|---|---|
| Definition | SEC63 homolog, protein translocation regulator |
| Date | Results | Publications |
|---|---|---|
| 2018-03-24 11:15:00 | Results suggest that loss of PRKCSH and SEC63 leads to general defects in ciliogenesis, while quenching of the Wnt signaling cascade is cholangiocyte-restricted. | 28973524 |
| 2013-06-29 12:11:00 | a SEC63 germline mutation may play a role in cyst formation in polycystic liver disease | 23209713 |
| 2013-06-22 11:01:00 | Phosphorylation of Sec63 by CK2 enhanced its binding to Sec62 | 23287549 |
| 2013-05-11 12:40:00 | Sec63 may perform a substrate-selective quantity control function during cotranslational endoplasmic reticulum import. | 23166619 |
| 2013-01-26 11:42:00 | Silencing the human SEC63 genes inhibits transport of only a subset of signal-peptide-containing precursor proteins to endoplasmic reticulum. | 22375059 |
| Type | IDs |
|---|---|
| Synonymous | DNAJC23, ERdj2, PCLD2, PRO2507, SEC63L |
| Gene |
UniProtKB-ID:
SEC63_HUMAN,
A0A0S2Z5M1_HUMAN
UniprotKB:
Q9UGP8,
A0A0S2Z5M1
UniParc:
UPI000000DBBB
EMBL:
AF100141,
AJ011779,
BC023598,
AL024507,
CH471051,
BC048287,
KU178551,
BC047221,
AL137338
Ensembl:
ENSG00000025796
KO:
hsa:11231
|
| Nucleutide sequences |
EMBL-CDS:
AAH48287.1,
AAC83375.1,
AAH23598.1,
CAB70701.1,
AAH47221.1,
CAB46275.1,
ALQ34009.1,
EAW48392.1
Gene_ORFName:
hCG_34021
Ensembl_TRS:
ENST00000369002
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357998
RefSeq:
XP_016865707.1,
NP_009145.1
|
| Others |
UniRef100:
UniRef100_Q9UGP8
UniRef90:
UniRef90_Q9UGP8
UniRef50:
UniRef50_Q9UGP8
UniGene:
Hs.26904
CCDS:
CCDS5061.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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