| Type | Description |
|---|---|
| Definition | Ras association domain family member 8 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 10:12:00 | data provide evidence that E4BP4 attenuates RASSF8-mediated anti-proliferation and apoptosis, shedding mechanistic insights into RASSF8 down-regulation in breast cancers. | 29467226 |
| 2018-10-27 11:59:00 | MiR-505 mediated MTX resistance, propagation, cell cycle and metastasis by targeting RASSF8 in colorectal cancer | 29726011 |
| 2018-08-11 11:46:00 | The miR-224 played an oncogenic role in the proliferation of NSCLC by direct targeting RASSF8. | 28770961 |
| 2017-08-05 12:40:00 | RASSF8 knockdown by specific showed similar effects in cervical cancer cells transfected with miR-224 mimic. Our findings suggest that miR-224 directly targets RASSF8 and thereby acts as a tumor promoter in cervical cancer progression | 27626930 |
| 2017-07-29 12:41:00 | These results indicate that hypoxia-inducible miR-224 promotes gastric cancer cell growth, migration and invasion by downregulating RASSF8 and acts as an oncogene, implying that inhibition of miR-224 may have potential as a therapeutic target for patients with hypoxic gastric tumors. | 28173803 |
| Type | IDs |
|---|---|
| Synonymous | C12orf2, HOJ1 |
| Gene |
UniProtKB-ID:
RASF8_HUMAN,
A0A024RB12_HUMAN,
A8K8G8_HUMAN
UniprotKB:
Q8NHQ8,
A0A024RB12,
A8K8G8
UniParc:
UPI00015DA9E2,
UPI00001FB7C1,
UPI000006E794
EMBL:
U82396,
AB093206,
AK290055,
AY665468,
AK292333,
BC030021,
CH471094
Ensembl:
ENSG00000123094
KO:
hsa:11228
|
| Nucleutide sequences |
EMBL-CDS:
AAV54603.1,
EAW96523.1,
BAF82744.1,
AAH30021.1,
BAC98838.1,
AAC95425.1,
EAW96524.1,
EAW96525.1,
BAF85022.1
Gene_ORFName:
hCG_38034
Ensembl_TRS:
ENST00000381352,
ENST00000542865,
ENST00000282884,
ENST00000615708,
ENST00000405154,
ENST00000541490
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000481417,
ENSP00000370756,
ENSP00000282884,
ENSP00000384491,
ENSP00000443096,
ENSP00000439839
RefSeq:
NP_001158219.1,
NP_001158220.1,
XP_024304588.1,
XP_006719090.1,
XP_024304586.1,
XP_006719091.1,
XP_024304587.1,
XP_016874235.1,
NP_001158218.1,
XP_024304590.1,
NP_009142.2,
XP_024304589.1
|
| Others |
UniRef100:
UniRef100_Q8NHQ8,
UniRef100_A8K8G8
UniRef90:
UniRef90_Q8NHQ8
UniRef50:
UniRef50_Q8NHQ8
UniGene:
Hs.696433
CCDS:
CCDS53765.1,
CCDS8705.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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