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112278 Pas1

112278

Pas1

pulmonary adenoma susceptibility 1

unknown

Mus musculus

基因描述

Type Description
Definition pulmonary adenoma susceptibility 1

研究结论

Date Results Publications
2017-12-02 12:19:00 The present study demonstrates that the SM/J strain carries, at the Pas1 locus, the resistance allele: a finding that will facilitate identification of the Pas1 causal element 28796413
2016-08-27 12:07:00 our results illustrate the architecture of germline control of gene expression in mouse lung cancer: they highlight the importance of Pas1 as a tumor-modifier locus, attribute to it a novel role as a major regulator of transcription in lung tumor 26966001
2010-01-21 00:00:00 The Pas1 locus covers a minimal region of 468 kb containing six genes: Bcat1, Lrmp, Las1, Ghiso, Lmnra-rs1, and Kras2, having a functional role for both intronic and exonic polymorphisms in lung tumor susceptibility. 15064703
2010-01-21 00:00:00 Cis-acting genomic elements of the Pas1 locus control Kras mutability in lung tumors. 18560355
2010-01-21 00:00:00 propose that the Pas1 modifier effect is due to Kras2, and that a sensitive balance between the expression levels of wild-type and mutant alleles determines lung tumor susceptibility 16823377

名称对应

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Type IDs
Synonymous Pas-1