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11226 GALNT6

11226

GALNT6

polypeptide N-acetylgalactosaminyltransferase 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition polypeptide N-acetylgalactosaminyltransferase 6

研究结论

Date Results Publications
2021-03-13 13:22:00 GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of alpha2M. 32559179
2021-03-13 13:18:00 GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78. 32393740
2020-10-24 14:02:00 The GALNT6LGALS3BP axis promotes breast cancer cell growth. 31894262
2019-11-09 10:25:00 the 15-glycogene signature and the expression levels of GALNT6 mRNA and protein each serve as a novel prognostic biomarker, highlighting the role of dysregulated glycogenes in cancer-associated glycan synthesis and poor prognosis 29844132
2019-08-31 11:32:00 We confirmed that GALNT3 gene ablation leads to strong and rather compensatory GALNT6 upregulation in EOC cells. Moreover, double GALNT3/T6 suppression was significantly associated with stronger inhibitory effects on EOC cell proliferation, migration, and invasion, and accordingly displayed a significant increase in animal survival rates compared with GALNT3-ablated and control (Ctrl) EOC cells. 31071912

名称对应

Type IDs
Synonymous GALNAC-T6, GalNAcT6
Gene
UniProtKB-ID: GALT6_HUMAN
UniprotKB: Q8NCL4
UniParc: UPI000013D726
EMBL: AK025961, Y08565, BC035822, AK074658
Ensembl: ENSG00000139629
KO: hsa:11226
Nucleutide sequences
EMBL-CDS: CAA69876.1, BAB15297.1, BAC11118.1, AAH35822.2
Ensembl_TRS: ENST00000356317, ENST00000543196
Protein sequencees
Ensembl_PRO: ENSP00000348668, ENSP00000444171
RefSeq: XP_024304584.1, XP_024304582.1, XP_006719277.1, NP_009141.2, XP_005268664.1, XP_024304580.1, XP_024304583.1, XP_024304585.1, XP_011536124.1, XP_011536121.1, XP_024304581.1, XP_016874234.1, XP_024304579.1
Others
UniRef100: UniRef100_Q8NCL4
UniRef90: UniRef90_Q8NCL4
UniRef50: UniRef50_Q8NCL4
UniGene: Hs.505575
CCDS: CCDS8813.1

全选

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