| Type | Description |
|---|---|
| Definition | adenylate cyclase 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 10:51:00 | Effect of Adenylyl Cyclase Type 6 on Localized Production of cAMP by beta-2 Adrenoceptors in Human Airway Smooth-Muscle Cells | 31068382 |
| 2019-12-21 10:36:00 | Data found that direct binding of 4.1G to the N-terminus of AC6 (AC6-N) contributes to the plasma membrane association of AC6-N and the resulting suppression of AC6 cyclase activity. | 31383768 |
| 2019-07-13 10:48:00 | PDE8 is expressed in lipid rafts of human airway smooth muscle cells(HASM), where it specifically regulates beta2-adrenergic receptor/ AC6 signaling to modulate HASM responsiveness and airway remodeling in asthma. | 29262264 |
| 2018-12-22 10:09:00 | rs3730071G/T and rs77913913G/T of ADCY6 were non-polymorphic with respect to HAPE. | 29443612 |
| 2018-11-03 10:48:00 | model suggests Cys1004 in AC6 (subunit C2) and Cys174 in Galphas present at the AC-Galphas interface as the possible residues that might undergo reversible nitrosylation. Docking analysis predicted novel ligands of AC6 that include forskolin-based compounds and its derivatives. | 29327289 |
| Type | IDs |
|---|---|
| Synonymous | AC6, LCCS8 |
| Gene |
UniProtKB-ID:
ADCY6_HUMAN
UniprotKB:
O43306
UniParc:
UPI000003EC29,
UPI000002A796
EMBL:
BC064923,
AB007882,
AF250226
Ensembl:
ENSG00000174233
KO:
hsa:112
|
| Nucleutide sequences |
EMBL-CDS:
BAA24852.2,
AAF82478.1
Ensembl_TRS:
ENST00000307885,
ENST00000550422,
ENST00000357869
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311405,
ENSP00000446730,
ENSP00000350536
RefSeq:
NP_056085.1,
XP_016874232.1,
XP_006719273.1
|
| Others |
UniRef100:
UniRef100_O43306
UniRef90:
UniRef90_O43306
UniRef50:
UniRef50_Q03343
UniGene:
Hs.525401,
Hs.694408
CCDS:
CCDS8767.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of California |
5 |
| 2 |
University of Texas Southwestern Medical Center |
3 |
| 3 |
University of Tennessee Health Science Center |
3 |
| 4 |
Baylor College of Medicine |
2 |
| 5 |
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Rennolds S Ostrom |
4 |
| 2 |
Steven P Gygi |
3 |
| 3 |
A G Gilman |
3 |
| 4 |
Joao A Paulo |
2 |
| 5 |
David E Hill |
2 |