| Type | Description |
|---|---|
| Definition | SPT16 homolog, facilitates chromatin remodeling subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:15:00 | Proteasomal Regulation of Mammalian SPT16 in Controlling Transcription. | 33526453 |
| 2020-05-02 10:42:00 | suggest a compelling mechanism for how FACT maintains chromatin integrity during polymerase passage, by facilitating removal of the H2A-H2B dimer, stabilizing intermediate subnucleosomal states and promoting nucleosome reassembly | 31775157 |
| 2019-11-30 11:08:00 | FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates transcription-coupled nucleotide excision repair. | 30715484 |
| 2019-09-21 12:30:00 | Spt16 N-terminal domain is a histone H3-H4-specific binding domain with a distinct mechanism of interaction between histones and histone chaperones. | 30528735 |
| 2019-03-16 11:12:00 | We suggested that this constituted a new multiple congenital anomaly-intellectual disability syndrome due to defects in CHD8 and/or SUPT16H..The identification of multiple patients with the same genetic defect and characteristic clinical phenotype, confirms our suggestion that this is a syndromic disorder caused by haploinsufficiency or heterozygous loss of function of CHD8. | 30670789 |
| Type | IDs |
|---|---|
| Synonymous | CDC68, FACTP140, SPT16, SPT16/CDC68 |
| Gene |
UniProtKB-ID:
SP16H_HUMAN
UniprotKB:
Q9Y5B9
UniParc:
UPI0000035D5C
EMBL:
BC064561,
AF164924,
BC073849,
AF152961,
BC014046,
BC000565
Ensembl:
ENSG00000092201
KO:
hsa:11198
|
| Nucleutide sequences |
EMBL-CDS:
AAF28231.1,
AAH00565.1,
AAD43978.1,
AAH14046.1,
AAH73849.1,
AAH64561.1
Ensembl_TRS:
ENST00000216297
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216297
RefSeq:
NP_009123.1,
XP_011534683.1
|
| Others |
UniRef100:
UniRef100_Q9Y5B9
UniRef90:
UniRef90_Q9Y5B9
UniRef50:
UniRef50_Q9Y5B9
UniGene:
Hs.213724
CCDS:
CCDS9569.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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