| Type | Description |
|---|---|
| Definition | choline kinase alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:18:00 | [Knockdown of choline kinase alpha (CHKA) inhibits the proliferation, invasion and migration of human U87MG glioma cells]. | 32958130 |
| 2019-10-05 12:38:00 | During proliferation, KDM2B binds to the Box2 located in the Chka promoter repressing its transcription. KDM2B knockdown enhances the levels of CKalpha expression in neuroblast cells and induces neuronal differentiation. These results suggest that KDM2B is required for the appropriate regulation of CKalpha during neuronal differentiation and to the maintaining of the undifferentiated stage of neuroblast cells. | 30629659 |
| 2018-09-22 11:43:00 | miR-876-5p was able to significantly decrease the expression level of choline kinase alpha mRNA. | 29568919 |
| 2018-08-04 11:52:00 | There is no correlation between single CHKA rs7928739 polymorphism and the incidence of intrauterine fetal death. | 28509322 |
| 2018-05-26 11:04:00 | This study presents the detail the 2.35 A structure of choline kinase alpha in complex with inhibitor TCD-717. | 29389115 |
| Type | IDs |
|---|---|
| Synonymous | CHK, CK, CKI, EK |
| Gene |
UniProtKB-ID:
CHKA_HUMAN
UniprotKB:
P35790
UniParc:
UPI000013D662,
UPI000035E2C8
EMBL:
AP002807,
D10704,
AP002992,
BC036471
Ensembl:
ENSG00000110721
KO:
hsa:1119
|
| Nucleutide sequences |
EMBL-CDS:
BAA01547.1,
AAH36471.1
Ensembl_TRS:
ENST00000265689,
ENST00000356135
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265689,
ENSP00000348454
RefSeq:
NP_001363151.1,
NP_001268.2,
NP_001363148.1,
NP_001363149.1,
NP_997634.1,
NP_001363150.1,
XP_016872637.1
|
| Others |
UniRef100:
UniRef100_P35790
UniRef90:
UniRef90_P35790
UniRef50:
UniRef50_P35790
UniGene:
Hs.77221
CCDS:
CCDS8179.1,
CCDS8178.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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