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11176 BAZ2A

11176

BAZ2A

bromodomain adjacent to zinc finger domain 2A

protein-coding

Homo sapiens

基因描述

Type Description
Definition bromodomain adjacent to zinc finger domain 2A

研究结论

Date Results Publications
2018-09-29 10:16:00 the results of the present study demonstrated that TIP5 regulates beta-catenin/TCF7L2 signaling via TIP5 during HCC progression and suggests that TIP5 may be a promising therapeutic target for the treatment of HCC. 29620186
2017-06-24 11:23:00 Data suggest that binding of helical tail of histone 3 (H3) with PHD ('plant homeodomain') fingers of BAZ2A or BAZ2B (bromodomain adjacent to zinc finger domain 2A or 2B) requires molecular recognition of secondary structure motifs within H3 tail and could represent an additional layer of regulation in epigenetic processes. 28341809
2015-10-31 11:04:00 Data show that SUMOylated BANP, E5R, and Nac1 (BEN) domain 3 (BEND3) stabilizes NoRC component TTF-1-interacting protein 5 (Tip5)via association with ubiquitin specific protease 21 (USP21) debiquitinase 26100909
2015-10-03 11:34:00 Crystal structures of PHD zinc finger and bromodomains from human TIP5 and BAZ2B in free form and bound to H3 and/or H4 histones. 25533489
2015-08-22 11:04:00 The study showed that the NMR structure of the TAM domain of TIP5 resembles the fold of the MBD domain, found in methyl-CpG binding proteins. 25916849

名称对应

Type IDs
Synonymous TIP5, WALp3
Gene
UniProtKB-ID: BAZ2A_HUMAN, F8VU39_HUMAN
UniprotKB: Q9UIF9, F8VU39
UniParc: UPI0001B04B96, UPI0000D4FED1, UPI000013F1F2, UPI0001B04B95
EMBL: CR749379, AK023830, AC090681, AB032254, AF000422, AB002312, BC008965
Ensembl: ENSG00000076108
KO: hsa:11176
Nucleutide sequences
EMBL-CDS: BAG51228.1, BAA89211.1, AAH08965.2, CAH18232.1, AAB60864.1, BAA20773.2
Ensembl_TRS: ENST00000551812, ENST00000549884
Protein sequencees
Ensembl_PRO: ENSP00000446880, ENSP00000447941
RefSeq: NP_001287834.1, XP_016874229.1, XP_011536108.1, XP_016874230.1, NP_001338085.1, XP_011536103.1, XP_011536107.1, NP_038477.2, XP_011536111.1, XP_011536105.1, XP_011536106.1
Others
UniRef100: UniRef100_Q9UIF9
UniRef90: UniRef90_Q9UIF9
UniRef50: UniRef50_Q91YE5
UniGene: Hs.314263
CCDS: CCDS44924.1

全选

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研究热度

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