例如:"NBL1", "4681", "drought"
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11170 FAM107A

11170

FAM107A

family with sequence similarity 107 member A

protein-coding

Homo sapiens

基因描述

Type Description
Definition family with sequence similarity 107 member A

研究结论

Date Results Publications
2019-06-22 10:38:00 Results showed that DRR1 is overexpressed in glioblastoma multiforme (GBM) tissues. Its overexpression is associated with tumor progression and poor clinical outcome of GBM patients, which indicates that DRR1 might be a novel prognostic marker of GBM. More results indicated that DRR1 was involved in GBM invasion and progression possibly through the induction of EMT as activated by phosphorylation of AKT. 29548818
2019-03-09 12:31:00 Both IQGAP3/BMP4 and IQGAP3/FAM107A ratios in ucfDNA were significantly higher in patients with BC than in those with hematuria. 30446454
2019-01-19 10:51:00 FAM107A gene is down-regulated in laryngeal tumors. 28710449
2017-10-28 10:45:00 This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 that is involved in NF-kappaB degradation and cell cycle suppression in neuroblastoma cells. 28604741
2015-09-12 10:47:00 Importance of FAM107A in lung carcinogenesis, although other than promoter hypermethylation mechanism of the gene decreased expression. 25753555

名称对应

Type IDs
Synonymous DRR1, TU3A
Gene
UniProtKB-ID: F107A_HUMAN, Q6IAM1_HUMAN, A0A024R327_HUMAN
UniprotKB: O95990, Q6IAM1, A0A024R327
UniParc: UPI0000E1FD7F, UPI0000071B73, UPI000020AE2A, UPI000012989D
EMBL: EU569833, AF089854, AK055443, BC010561, CH471055, CR457133, AC116036, AF089853, AK316450, AB023811, AB023810, AC119424, AL050264, AK054720
Ensembl: ENSG00000168309
KO: hsa:11170
Nucleutide sequences
EMBL-CDS: BAB70924.1, AAH10561.1, EAW65380.1, BAA83072.1, BAA82845.1, BAG51416.1, CAB43366.1, AAD16093.1, AAD16094.1, BAH14821.1, EAW65378.1, CAG33414.1, ACB71116.1, EAW65381.1
Gene_ORFName: hCG_22019, hCG_22019
Ensembl_TRS: ENST00000394481, ENST00000474531, ENST00000447756, ENST00000649301, ENST00000360997, ENST00000464064
Protein sequencees
Ensembl_PRO: ENSP00000419124, ENSP00000497152, ENSP00000400858, ENSP00000354270, ENSP00000419529, ENSP00000377991
RefSeq: NP_001269642.1, NP_001070246.1, NP_001269643.1, NP_009108.1
Others
UniRef100: UniRef100_O95990
UniRef90: UniRef90_O95990
UniRef50: UniRef50_O95990
UniGene: Hs.506357
CCDS: CCDS63672.1, CCDS63673.1, CCDS2892.1

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