| Type | Description |
|---|---|
| Definition | follistatin like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | Follistatin-like 1: A dual regulator that promotes cardiomyocyte proliferation and fibrosis. | 32017077 |
| 2021-02-13 13:29:00 | Circular RNA hsa_circ_0004812 impairs IFN-induced immune response by sponging miR-1287-5p to regulate FSTL1 in chronic hepatitis B. | 32188476 |
| 2020-07-04 10:53:00 | Within the COPDGene cohort, several SNPs in the FSTL1 region corresponded to chronic obstructive pulmonary disease and lung function. | 31834999 |
| 2020-05-30 10:55:00 | The Fstl1-FK forms a stable dimer in both solution and crystal, which suggest that this protein may function as a dimer during its interaction with TGF-beta, a molecule known to form dimer during activation process. | 31351024 |
| 2020-05-30 10:55:00 | Reduced levels of FSTL1 were detected in various tumors and were associated with poor clinical outcome in patients with non-small cell lung cancer. FSTL1 expression negatively correlated with the metastatic potential of lung cancer cells. FSTL1 directly bound to the proform of SPP1/osteopontin, restraining proteolytic activation of SPP1, which led to inactivation of integrin/CD44-associated signaling. | 31653686 |
| Type | IDs |
|---|---|
| Synonymous | FRP, FSL1, MIR198, OCC-1, OCC1, tsc36 |
| Gene |
UniProtKB-ID:
FSTL1_HUMAN
UniprotKB:
Q12841
UniParc:
UPI00017A7E72,
UPI00000422DB
EMBL:
D89937,
AB119283,
BC000055,
AK300356,
AC063952,
AK312261,
AK291138,
CH471052,
AC078982,
U06863,
AK289388
Ensembl:
ENSG00000163430
KO:
hsa:11167
|
| Nucleutide sequences |
EMBL-CDS:
BAG62097.1,
EAW79527.1,
AAA66062.1,
BAF83827.1,
BAA28707.1,
BAD12167.1,
AAH00055.1,
EAW79526.1,
BAF82077.1,
BAG35192.1
Ensembl_TRS:
ENST00000295633,
ENST00000424703
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295633,
ENSP00000394355
RefSeq:
XP_024309095.1,
NP_009016.1
|
| Others |
UniRef100:
UniRef100_Q12841
UniRef90:
UniRef90_Q12841
UniRef50:
UniRef50_Q12841
UniGene:
Hs.269512
CCDS:
CCDS2998.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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