| Type | Description |
|---|---|
| Definition | FIC domain containing |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:47:00 | A Fluorescence Polarization-Based High-Throughput Screen to Identify the First Small-Molecule Modulators of the Human Adenylyltransferase HYPE/FICD. | 32992526 |
| 2020-04-11 11:12:00 | FICD-dependent AMPylation remodelling accelerates differentiation of neural progenitor cells into mature neurons. | 31980631 |
| 2017-07-08 10:20:00 | The single catalytic domain of FICD can release the attached AMP, restoring functionality to BiP. | 27918543 |
| 2016-10-22 12:32:00 | We first demonstrate efficient enrichment and fast visualization of potential HYPE substrates in cell lysates by in-gel fluorescence, followed by robust identification via shotgun proteomics on a QExactive mass spectrometer | 26604261 |
| 2015-06-06 10:23:00 | HYPE is an unfolded protein response regulator. | 25601083 |
| Type | IDs |
|---|---|
| Synonymous | HIP13, HYPE, UNQ3041 |
| Gene |
UniProtKB-ID:
FICD_HUMAN,
A0A024RBM8_HUMAN
UniprotKB:
Q9BVA6,
A0A024RBM8
UniParc:
UPI0000048F49
EMBL:
BC001342,
AF049611,
AY358992,
CH471054
Ensembl:
ENSG00000198855
KO:
hsa:11153
|
| Nucleutide sequences |
EMBL-CDS:
AAH01342.2,
AAQ89351.1,
AAC26847.1,
EAW97813.1,
EAW97815.1
Gene_ORFName:
UNQ3041/PRO9857,
hCG_15699
Ensembl_TRS:
ENST00000552695
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000446479
RefSeq:
NP_009007.2
|
| Others |
UniRef100:
UniRef100_Q9BVA6
UniRef90:
UniRef90_Q9BVA6
UniRef50:
UniRef50_Q9BVA6
UniGene:
Hs.661891
CCDS:
CCDS9116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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