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111507 Igh

111507

Igh

immunoglobulin heavy chain complex

protein-coding

Mus musculus

基因描述

Type Description
Definition immunoglobulin heavy chain complex

研究结论

Date Results Publications
2021-03-13 13:25:00 Loop extrusion mediates physiological Igh locus contraction for RAG scanning. 33442057
2020-12-26 13:15:00 CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining. 32989150
2015-10-03 10:56:00 Each of the two Igh alleles in a B cell behaves independently of the other, up to the moment when a successful rearrangement in one allele triggers a feedback mechanism that prevents further recombination. 25517887
2015-07-25 11:10:00 Data indicate that a regulatory element within the immunoglobulin heavy chain gene (3'IghRR) is a target of the aryl hydrocarbon receptor (AhR). 25749007
2014-03-29 11:13:00 Focused AgR chromatin analysis splits the Igh-SE into 2 active regions that belong to states 4 and 5. Only the hRE1 region functions as an enhancer in pro-B cells. It interacts with other Igh regulatory elements. hRE2 belongs to state 5. 24353267

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