| Type | Description |
|---|---|
| Definition | HERV-H LTR-associating 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:33:00 | Results found HHLA2 more commonly expressed and possesses significant prognostic value compared with PD-L1 in intrahepatic cholangiocarcinoma (ICC) cases. High HHLA2 is frequent in PD-L1 negative cases and is associated with fewer infiltrating cytotoxic and regulatory T cells. | 30885276 |
| 2020-04-25 11:01:00 | Increased HHLA2 expression was observed in ccRCC tumour tissue, which leads to a remarkable shorter overall survival and poorer prognosis. Together with other molecular evidence, we have demonstrated that HHLA2 could be a potential prognostic biomarker for ccRCC. | 29967134 |
| 2020-04-18 11:20:00 | Low HHLA2 expression is associated with malignant glioma. | 31578594 |
| 2020-01-04 11:49:00 | Kaplan-Meier survival curve revealed that high HHLA2 expression was significantly correlated with the poor RFS and OS of BUC patients (both p < 0.05), and the ROC curve showed HHLA2 could be a good diagnostic marker | 30602154 |
| 2019-11-02 10:52:00 | Up-regulation of HHLA2, a novel immune checkpoint protein, in pancreatic ductal adenocarcinoma predicts post-surgical survival. | 30447255 |
| Type | IDs |
|---|---|
| Synonymous | B7-H5, B7-H7, B7H7, B7y |
| Gene |
UniProtKB-ID:
HHLA2_HUMAN,
C9J7D0_HUMAN
UniprotKB:
Q9UM44,
C9J7D0
UniParc:
UPI0000073CD9,
UPI0001B794DA,
UPI00017A7469
EMBL:
AK296644,
AK000692,
AC135308,
AF126162,
CH471052,
BC035971,
AC078855
Ensembl:
ENSG00000114455
KO:
hsa:11148
|
| Nucleutide sequences |
EMBL-CDS:
AAH35971.1,
EAW79727.1,
AAD48396.1,
BAG59244.1,
BAA91323.1,
EAW79728.1
Ensembl_TRS:
ENST00000357759,
ENST00000489514,
ENST00000619531,
ENST00000467562,
ENST00000467761,
ENST00000491820
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000417856,
ENSP00000350402,
ENSP00000419207,
ENSP00000482187,
ENSP00000418345,
ENSP00000418284
RefSeq:
XP_011510669.1,
XP_011510665.1,
NP_001269487.1,
XP_011510666.1,
XP_005247137.1,
NP_001269488.1,
NP_009003.1,
XP_024309094.1,
NP_001269486.1,
NP_001269485.1,
XP_011510664.1,
NP_001357173.1
|
| Others |
UniRef100:
UniRef100_Q9UM44,
UniRef100_C9J7D0
UniRef90:
UniRef90_Q9UM44
UniRef50:
UniRef50_Q9UM44
UniGene:
Hs.252351
CCDS:
CCDS46883.1,
CCDS63713.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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